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Dipotassium glycyrrhizinate

Cat. No. M13497
Dipotassium glycyrrhizinate Structure
Synonym:

Glycyrrhizic acid dipotassium; Dipotassium glycyrrhizate

Size Price Availability Quantity
100mg USD 50  USD50 In stock
500mg USD 110  USD110 In stock
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Quality Control & Documentation
Biological Activity

Dipotassium glycyrrhizinate is a natural compound, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity.

Chemical Information
Molecular Weight 899.11
CAS Number 68797-35-3
Solubility (25°C) Water 50 mg/mL
DMSO 5 mg/mL
Storage 2-8°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Camila Dos Santos Leite, et al. Acta Cir Bras. Effects of dipotassium glycyrrhizinate on wound healing

[2] Keisuke Matsuoka, et al. J Oleo Sci. Micelle Formation of Monoammonium Glycyrrhizinate

[3] Hiromi Taninokuchi, et al. Oral Health Prev Dent. Evaluation of a Cetylpyridinium Chloride-, Dipotassium Glycyrrhizinate-, and Tranexamic Acid-based Mouthwash after Implant Placement: A Double-blind Randomised Clinical Trial

[4] Tianbao Lv, et al. Microb Pathog. Dipotassium glycyrrhizinate relieves leptospira-induced nephritis in vitro and in vivo

[5] Zhi-Gang Sun, et al. Mini Rev Med Chem. Research Progress of Glycyrrhizic Acid on Antiviral Activity

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Keywords: Dipotassium glycyrrhizinate, Glycyrrhizic acid dipotassium; Dipotassium glycyrrhizate supplier, inhibitors, activators


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