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Natural Products

Cat.No.  Name Information
M4022 Hypaconitine Hypaconitine is a highly toxic natural active ingredient isolated from aconitum species, which is widely used to study rheumatism.
M4021 Mesaconitine Mesaconitine is the main active ingredient of Aconitum and has many pharmaceutical effects.
M4020 Bulleyaconi-cine-A Bulleyaconitine A, A compound isolated from aconite, has anti-inflammatory activity and can also be used in pain relief studies.
M4019 Songorine Songorine is a diterpenoid alkaloid isolated from the genus Aconite. Songorine is a GABAA receptor antagonist in rat brain and has anticancer, anti-arrhythmia and anti-inflammatory activities. Songorine has potential to be used in epithelial ovarian cancer (EOC) studies.
M4018 Benzoylhypacoitine Benzoylhypaconine (Benzoylhypacoitine) is a monoester alkaloid in Aconitum, which is the main pharmacological and toxic component of Aconitum.
M4017 Benzoylmesaconine Benzoylmesaconine (Mesaconine 14-Benzoate) is the most abundant component of aconite soup, which can be used in studies of rheumatoid arthritis.
M4016 Benzoylaconine Benzoylaconine (Isaconitine; Pikraconitin) is a alkaloid of Aconite.
M4014 Licochalcone-C Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. Licochalcone-C is an inhibitor of lipopolysaccharide-interferon-γ inflammation.
M4013 Glabridin Glabridin, one of the active phytochemicals in licorice extract, binds to and activates the ligand binding domain of PPARγ, as well as the full length receptor. It is also a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory.
M4012 Licochalcone-A Licochalcone A is an estrogenic flavonoid derived from licorice that induces Nrf2-mediated defense mechanisms and ameliorates acetaminophen and endotoxin-induced liver injury. In addition, Licochalcone A has antimalarial, anticancer, antibacterial and antiviral activities.
M4011 Echinatin Echinatin is isolated from the Chinese herbal medicine licorice, chalcone, which has liver protection and anti-inflammatory effects. In rats, Echinatin can be rapidly absorbed and eliminated and is widely distributed, with an absolute bioavailability of about 6.81%.
M4010 Isoliquiritigenin Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza glabra, which inhibits aldose reductase with an IC50 of 320 nM.
M4009 Licochalcone-B Licochalcone A is a chalconoid, a type of natural phenols. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata.
M4008 Liquiritigenin Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β (ERβ) agonist with an EC50 of 36.5 nM for activation of the ERE tk-Luc.
M4007 Isoliquiritin Isoliquiritin is isolated from licorice root and inhibits angiogenesis and duct formation. Isoliquiritin also has antidepressant and antifungal activity.
M4006 Monoammonium glycyrrhizinate Monoammonium glycyrrhizinate has various pharmacological actions such as anti-inflammatory, antiallergic, antigastriculcer, and antihepatitis activities.
M4004 Hyperoside Hyperoside is a potent natural activator of Nur77 receptor, which can be potentially used for the research of occlusive vascular diseases. Hyperoside is also a NF-κB inhibitor. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis.
M4003 Isoquercitrin Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway. Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system.
M4002 Chrysophanic acid Chrysophanic acid, also known as chrysophanol, is a fungal isolate and a natural anthraquinone with anti-cancer activity.
M4001 Aloe-emodin Aloe-emodin (AE), a hydroxyanthraquinone present in Aloe vera leaves, has a specific in vitro and in vivo antineuroectodermal tumor activity. Aloe-emodin can bind with mTORC2 and inhibit its kinase activity.

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