| Cat.No. | Name | Information |
|---|---|---|
| M4016 | Benzoylaconine | Benzoylaconine (Isaconitine; Pikraconitin) is a alkaloid of Aconite. |
| M4014 | Licochalcone-C | Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. Licochalcone-C is an inhibitor of lipopolysaccharide-interferon-γ inflammation. |
| M4013 | Glabridin | Glabridin, one of the active phytochemicals in licorice extract, binds to and activates the ligand binding domain of PPARγ, as well as the full length receptor. It is also a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory. |
| M4012 | Licochalcone-A | Licochalcone A is an estrogenic flavonoid derived from licorice that induces Nrf2-mediated defense mechanisms and ameliorates acetaminophen and endotoxin-induced liver injury. In addition, Licochalcone A has antimalarial, anticancer, antibacterial and antiviral activities. |
| M4011 | Echinatin | Echinatin is isolated from the Chinese herbal medicine licorice, chalcone, which has liver protection and anti-inflammatory effects. In rats, Echinatin can be rapidly absorbed and eliminated and is widely distributed, with an absolute bioavailability of about 6.81%. |
| M4010 | Isoliquiritigenin | Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza glabra, which inhibits aldose reductase with an IC50 of 320 nM. |
| M4009 | Licochalcone-B | Licochalcone A is a chalconoid, a type of natural phenols. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata. |
| M4008 | Liquiritigenin | Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β (ERβ) agonist with an EC50 of 36.5 nM for activation of the ERE tk-Luc. |
| M4007 | Isoliquiritin | Isoliquiritin is isolated from licorice root and inhibits angiogenesis and duct formation. Isoliquiritin also has antidepressant and antifungal activity. |
| M4006 | Monoammonium glycyrrhizinate | Monoammonium glycyrrhizinate has various pharmacological actions such as anti-inflammatory, antiallergic, antigastriculcer, and antihepatitis activities. |
| M4004 | Hyperoside | Hyperoside is a potent natural activator of Nur77 receptor, which can be potentially used for the research of occlusive vascular diseases. Hyperoside is also a NF-κB inhibitor. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis. |
| M4003 | Isoquercitrin | Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway. Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. |
| M4002 | Chrysophanic acid | Chrysophanic acid, also known as chrysophanol, is a fungal isolate and a natural anthraquinone with anti-cancer activity. |
| M4001 | Aloe-emodin | Aloe-emodin (AE), a hydroxyanthraquinone present in Aloe vera leaves, has a specific in vitro and in vivo antineuroectodermal tumor activity. Aloe-emodin can bind with mTORC2 and inhibit its kinase activity. |
| M4000 | (±)-Naringenin | (±)-Naringenin, a common dietary flavonoid abundantly present in fruits and vegetables, is believed to possess strong anti-proliferative properties and the ability to induce apoptosis in hepatoma cell lines. |
| M3999 | Isorhamnetin | Isorhamnetin (Iso) is a flavonoid compound extracted from the Chinese herb Hippophae rhamnoides L. Previous studies have revealed its anti-cancer, anti-inflammatory, and anti-oxidant activities. Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3K. |
| M3997 | Nuciferine | Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM). Nuciferine possesses anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, and insulin secretagogue activities. |
| M3996 | Betulin | Betulin is a specific, small molecule inhibitor of SREBP (Sterol Regulatory Element-Binding Proteins). |
| M3995 | Jervine | Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog signaling. |
| M3994 | Hederagenin | Hederagenin is a derivative of oleanolic acid isolated from the leaves of ivy (Hedera helix L.) that has been shown to have potential anti-tumor activity. Hederagenin can inhibit LPS-stimulated expression of iNOS, COX-2, and NF-κB. |
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