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Ginsenoside-Rg5

Cat. No. M4090

All AbMole products are for research use only, cannot be used for human consumption.

Ginsenoside-Rg5 Structure
Size Price Availability Quantity
5mg USD 325  USD325 In stock
10mg USD 520  USD520 In stock
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Quality Control & Documentation
Biological Activity

Ginsenoside Rg5 is the main ingredient of red ginseng. Ginsenoside Rg5 blocks the binding of IGF-1 to its receptor with an IC50 of about 90 nM. Ginsenoside Rg5 also inhibited COX-2 mRNA expression by inhibiting DNA binding activity of NF-κB P65.

Chemical Information
Molecular Weight 767.00
Formula C42H70O12
CAS Number 186763-78-0
Form Solid
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yanyan Zhu, et al. Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice

[2] Ming-Yang Liu, et al. Ginsenoside Rg5 Inhibits Human Osteosarcoma Cell Proliferation and Induces Cell Apoptosis through PI3K/Akt/mTORC1-Related LC3 Autophagy Pathway

[3] Ming-Yang Liu, et al. Pharmacological activities of ginsenoside Rg5 (Review)

[4] Leixin Song, et al. Ginsenoside Rg5 inhibits cancer cell migration by inhibiting the nuclear factor-κB and erythropoietin-producing hepatocellular receptor A2 signaling pathways

[5] Xiang-Yu Zhao, et al. Effects of ginsenoside Rg5 on cell cycle and invasion of gastric cancer

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Keywords: Ginsenoside-Rg5 supplier, IGF-1R, inhibitors, activators

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