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Ginsenoside-Rk1

Cat. No. M4092

All AbMole products are for research use only, cannot be used for human consumption.

Ginsenoside-Rk1 Structure
Size Price Availability Quantity
5mg USD 110  USD110 In stock
10mg USD 185  USD185 In stock
20mg USD 300  USD300 In stock
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Quality Control & Documentation
Biological Activity

Ginsenoside Rk1 is a high-temperature processed extract of ginseng. Ginsenoside Rk1 has anti-inflammatory effects and inhibits Jak2/Stat3 signaling pathway and NF-κB activation. Ginsenoside Rk1 has anti-tumor effects, anti-platelet aggregation activity, anti-inflammatory effects, anti-insulin resistance, renal protection, antibacterial effects, enhanced cognitive function, reduced lipid accumulation and prevention of osteoporosis. Ginsenoside Rk1 induces apoptosis by triggering intracellular reactive oxygen species (ROS) generation and blocking the PI3K/Akt pathway.

Chemical Information
Molecular Weight 766.998
Formula C42H70O12
CAS Number 494753-69-4
Form Solid
Solubility (25°C) 10 mM in DMSO
Storage -20°C, protect from light
References

[1] Jian Xiong, et al. Ginsenoside Rk1 protects human melanocytes from H 2 O 2‑induced oxidative injury via regulation of the PI3K/AKT/Nrf2/HO‑1 pathway

[2] Jung-Hae Shin, et al. Ginsenoside Rk1 suppresses platelet mediated thrombus formation by downregulation of granule release and α IIb β 3 activation

[3] Zhiman Li, et al. Ginsenoside Rk1 alleviates LPS-induced depression-like behavior in mice by promoting BDNF and suppressing the neuroinflammatory response

[4] Nayeon Ryoo, et al. Ginsenoside Rk1 is a novel inhibitor of NMDA receptors in cultured rat hippocampal neurons

[5] Manling Hu, et al. Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma

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Keywords: Ginsenoside-Rk1 supplier, NF-κB, inhibitors, activators

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