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Natural Products

Cat.No.  Name Information
M4099 Saikosaponin-B2 Saikosaponin B2, an active ingredient isolated from Bupleurum chinense, is an invasion inhibitor of HCV virus infection. Anti-cancer effect.
M4098 Saikosaponin-B1 Saikosaponin B1 is a bioactive ingredient of Bupleurum chinense with anticancer activity. Saikosaponin B1 significantly inhibits tumor growth in medulloblastoma (MB) models by targeting SMO to inhibit Hedgehog pathway.
M4096 Saikosaponin-C Saikosaponin C, the active ingredient in Bupleurum, mainly targets amyloid beta and tau proteins in ALZHEIMER's disease. Saikosaponin C inhibited the release of Aβ1-40 and Aβ1-42, and inhibited abnormal tau phosphorylation, but had no effect on BACE1 activity and expression.
M4095 Notoginsenoside-Fe Notoginsenoside Fe(Notoginsenoside Fe) is a natural compound isolated from the varieties of Marsupium.
M4094 Panaxtriol Panaxatriol is a natural product that reduces bone marrow suppression due to radiation damage.
M4093 Panaxadiol Panaxadiol exists in ginseng root and has neuroprotective and anti-tumor functions. Panaxadiol inhibits the expression of programmed cell death ligand-1 (PD-L1) and tumor proliferation.
M4092 Ginsenoside-Rk1 Ginsenoside Rk1 is a high-temperature processed extract of ginseng. Ginsenoside Rk1 has anti-inflammatory effects and inhibits Jak2/Stat3 signaling pathway and NF-κB activation.
M4091 Ginsenoside-Rg6 Ginsenoside Rg6 inhibited NF-κB transcriptional activity induced by TNF-α in HepG2 cells with IC50 of 29.34 μM. Ginsenoside Rg6 also induced apoptosis.
M4090 Ginsenoside-Rg5 Ginsenoside Rg5 is the main ingredient of red ginseng. Ginsenoside Rg5 blocks the binding of IGF-1 to its receptor with an IC50 of about 90 nM. Ginsenoside Rg5 also inhibited COX-2 mRNA expression by inhibiting DNA binding activity of NF-κB P65.
M4089 Ginsenoside-Ro Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) has the antiplatelet effect of Ca2+ antagonist with IC50 of 155 μM. Ginsenoside Ro decreased TXA2 production and Ginsenoside Ro also slightly decreased COX-1 and TXAS activity.
M4088 Ginsenoside Compound-K Ginsenoside Compound-K is a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2.
M4087 Ginsenoside-F5 Ginsenoside F5, which was obtained from Panax ginseng, significantly inhibited the growth of HL-60 cells through apoptosis pathway.
M4086 Ginsenoside-F4 Ginsenoside F4 (GF4), Ginsenoside, isolated from Panax notoginseng or red ginseng. Ginsenoside F4 (GF4) can inhibit human lymphocytic tumor JK cells by inducing apoptosis. Ginsenoside F4 (GF4) inhibited the expression of matrix metalloproteinase 13 (MMP 13) in IL-1β -treated chondrocytes, blocked cartilage damage in rabbit cartilage tissue culture, and prevented cartilage collagen matrix decomposition in pathological tissues.
M4085 Ginsenoside-F3 Ginsenoside F3, a saponin extracted from Panax ginseng leaves, exerts immune-enhancing activity by regulating the production and expression of il-2 (IFN-γ) and IL-4 and IL-10.
M4084 Ginsenoside-F2 Ginsenoside F2, a metabolite of Ginsenoside Rb1, induces apoptosis and protective autophagy in breast cancer stem cells.
M4083 Ginsenoside-F1 Ginsenoside F1 is an enzymatically modified derivative of Ginsenoside Rg1. Ginsenoside F1 competently inhibits CYP3A4 and has a weak inhibitory effect on CYP2D6.
M4082 Protopanaxtriol 20(R)-Protopanaxatriol is a natural ginsenoside ligand of Re, Rf, Rg1, Rg2 and Rh.
M4081 (R)Ginsenoside-Rg3 (20R) -Ginsenoside Rg3 ((20R)-Propanaxadiol), an active compound from ginseng root, has inhibitory effects on vascular endothelial cell proliferation (IC50= 10 nM) and antitumor activity.
M4080 (R)Ginsenoside-Rg2 20(R) -ginsenoside Rg2 is a Ginsenoside. 20(R)-Ginsenoside Rg2 has an inhibitory effect on lung cancer NCI-H1650 cells. It has anti-cancer activity.
M4079 (R)Ginsenoside-Rh2 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as an anti-proliferative agent in cells. It has anticancer effects by blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis and has anti-inflammatory and antioxidant activities. 20(R)-Ginsenoside Rh2 inhibited the replication and proliferation of mouse and human γ herpevirus 68 (MHV-68) with an IC50 of 2.77 μM against mouse MHV-68.

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