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Notoginsenoside Ft1(Notoginsenoside Ft1) is a plant isolated panax Notoginsenoside that stimulates angiogenesis. Ft1 induces the activation of PI3K/AKT and Raf/MEK/ERK signaling pathways. Ft1 caused endothelium-dependent relaxations, which were abolished by l-NAME (inhibitor of nitric oxide synthases) and ODQ (inhibitor of soluble guanylyl cyclase). Ft1 increased the cGMP level in rat mesenteric arteries.
| Molecular Weight | 917.13 |
| Formula | C47H80O17 |
| CAS Number | 155683-00-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 5 mg/mL |
| Storage | 4°C, sealed |
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