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Ginsenoside-F4

Cat. No. M4086

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Ginsenoside-F4 Structure
Size Price Availability Quantity
10mg USD 500  USD500 In stock
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Quality Control & Documentation
Biological Activity

Ginsenoside F4 (GF4), Ginsenoside, isolated from Panax notoginseng or red ginseng. Ginsenoside F4 (GF4) can inhibit human lymphocytic tumor JK cells by inducing apoptosis. Ginsenoside F4 (GF4) inhibited the expression of matrix metalloproteinase 13 (MMP 13) in IL-1β -treated chondrocytes, blocked cartilage damage in rabbit cartilage tissue culture, and prevented cartilage collagen matrix decomposition in pathological tissues.

Chemical Information
Molecular Weight 766.99
Formula C42H70O12
CAS Number 181225-33-2
Form Solid
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Qi-le Zhou, et al. Chemical constituents of Chinese red ginseng

[2] Wen-Wen Shen, et al. Biotransformation of ginsenosides F 4 and Rg 6 in zebrafish

[3] Je Hyeong Lee, et al. Ginsenosides from Korean red ginseng inhibit matrix metalloproteinase-13 expression in articular chondrocytes and prevent cartilage degradation

[4] Bin Chen, et al. The apoptosis-inducing effect of ginsenoside F4 from steamed notoginseng on human lymphocytoma JK cells

[5] Gui-Ying Liu, et al. Three new dammarane-type triterpene saponins from the leaves of Panax ginseng C.A. Meyer

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Keywords: Ginsenoside-F4 supplier, Apoptosis, inhibitors, activators

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