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Liquiritigenin

Cat. No. M4008

All AbMole products are for research use only, cannot be used for human consumption.

Liquiritigenin Structure
Synonym:

4',7-Dihydroxyflavanone

Size Price Availability Quantity
5mg USD 50 In stock
10mg USD 68 In stock
20mg USD 108 In stock
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Quality Control & Documentation
Biological Activity

Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β (ERβ) agonist with an EC50 of 36.5 nM for activation of the ERE tk-Luc.

Chemical Information
Molecular Weight 256.25
Formula C15H12O4
CAS Number 578-86-9
Form Solid
Solubility (25°C) 150 mg/mL in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mami Kato, et al. The Calcium-Activated Chloride Channel TMEM16A is Inhibitied by Liquiritigenin

[2] Chang-Can Shi, et al. Development of liquiritigenin-phospholipid complex with the enhanced oral bioavailability

[3] Fang Liang, et al. Liquiritigenin decreases tumorigenesis by inhibiting DNMT activity and increasing BRCA1 transcriptional activity in triple-negative breast cancer

[4] Marta Carnovali, et al. Liquiritigenin reduces osteoclast activity in zebrafish model of glucocorticoid-induced osteoporosis

[5] Eun Hye Lee, et al. Liquiritigenin inhibits hepatic fibrogenesis and TGF-β1/Smad with Hippo/YAP signal

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Keywords: Liquiritigenin, 4',7-Dihydroxyflavanone supplier, Estrogen Receptor, inhibitors, activators

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