About 30 results found for searched term "c-Myc" (0.01 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1969 | Doxorubicin HCL | Animal Modeling |
| RP 13057 hydrochloride; Adriamycin; Hydroxydaunorubicin hydrochloride; ADR; DOX | ||
| Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. | ||
| M2009 | Teicoplanin | Antibiotic |
| MDL-507; Targocid; Teichomycin | ||
| Teicoplanin is a long-acting glycopeptide antibiotic derived from actinomycetes that inhibits cell wall synthesis and interferes with the process of synthesizing new portions of peptidoglycan, and has a good inhibitory effect on gram-positive pathogens (including staphylococcal biofilms). | ||
| M2291 | Azacitidine | DNA/RNA Synthesis |
| 5-azacytidine; Ladakamycin; 5-AzaC; 5-AZA | ||
| Azacitidine is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases. | ||
| M2327 | Daunorubicin hydrochloride | DNA/RNA Synthesis |
| Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride | ||
| Daunorubicin (Daunomycin) HCl is a topoisomerase II inhibitor, inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. | ||
| M2488 | Capreomycin Sulfate | Antibiotic |
| Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit. | ||
| M2527 | Clindamycin | Antibiotic |
| Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin inhibits protein synthesis by acting on the 50S ribosomal. | ||
| M3235 | Clarithromycin | Cytochrome P450 (e.g. CYP17) |
| Clarithromycin is a macrolide antibiotic and a CYP3A4 inhibitor. | ||
| M3290 | Nystatin | Antibiotic |
| Fungicidin; Mycostatin | ||
| Nystatin (Fungicidin) is a polyene antifungal antibiotic to which many molds, mycoplasma and yeasts are sensitive, including Candida spp. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion. | ||
| M3494 | Lincomycin hydrochloride | Antibiotic |
| U10149A | ||
| Lincomycin hydrochloride is a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis. | ||
| M3533 | Spectinomycin hydrochloride | Antibiotic |
| Actinospectacin | ||
| Spectinomycin hydrochloride is a new parenteral antibiotic prepared from Streptomyces spectabilis. | ||
| M3536 | Clindamycin hydrochloride | Antibiotic |
| Clindamycin hydrochloride is the hydrated hydrochloride salt of clindamycin which is a semisynthetic antibiotic. | ||
| M3623 | A23187 | CaMK |
| Calcimycin | ||
| Calcimycin (A-23187) is a calcium ionophore that induces Ca2+-dependent cell death by increasing intracellular calcium concentration. A23187 is also an exosome release enhancer that promotes exosome secretion by increasing intracellular Ca²⁺ concentrations. Studies have shown that overnight treatment with 0.5 μM A23187 significantly increases exosome release in Jurkat cells. | ||
| M11542 | Ochromycinone | STAT |
| (Rac)-STA-21；STA 21 | ||
| Ochromycinone ((RAC-STA-21) is a natural antibiotic and a selective inhibitor of STAT3. Ochromycinone can inhibit STAT3 DNA binding activity and STAT3 dimerization. Ochromycinone has anticancer and antibacterial activities. | ||
| M3749 | Pentostatin | Adenosine Deaminase |
| Deoxycoformycin; CI-825 | ||
| Pentostatin (Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase (Ki = 2.5 pM). | ||
| M3807 | Ionomycin (Calcium salt) | Calcium Channel |
| Calcium ionomycin | ||
| Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. | ||
| M4798 | Tunicamycin | Transferase |
| NSC 177382, TN | ||
| Tunicamycin is a mixture of nucleoside antibiotics that inhibits N-glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin can cause the accumulation of unfolded proteins within the endoplasmic reticulum (ER) and induce ER stress, leading to impaired DNA synthesis and G1 phase cell cycle arrest. | ||
| M4849 | 7-Aminoactinomycin D | Nucleic Acid Staining |
| 7-AAD | ||
| 7-aminoactinomycin D (7-aad) can bind to DNA, and the maximum excitation/emission wavelength is 546nm/647 nm. The best excitation laser is 561nm or 488nm. It gives red fluorescence and is often used to observe the nucleus and nucleic acid. Store in freezer (-5 to -30°C) away from light. The solvent was DMSO. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M4862 | Vancomycin HCl | Antibiotic |
| Vancocin HCl | ||
| Vancomycin HCl is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent. Vancomycin hydrochloride acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis. | ||
| M4904 | Clindamycin Phosphate | Antibiotic |
| NSC 618653 | ||
| Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM. | ||
| M5422 | Ascomycin | Anti-infection |
| FK520; FR 900520, Immunomycin | ||
| Ascomycin (FK520), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3. | ||
| M5527 | Clindamycin palmitate HCl | Antibiotic |
| Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic. | ||
| M5743 | Lincomycin hydrochloride monohydrate | Antibiotic |
| Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic, has similar effects to erythromycin, which has a good effect on gram-positive coccus, mainly used to inhibit the synthesis of bacterial cell protein. | ||
| M5825 | Novobiocin Sodium | Topoisomerase |
| Albamycin; Cathomycin | ||
| Novobiocin Sodium is an aminocoumarin antibiotic that targets bacterial DNA gyrase (TopoIV), used to treat susceptible gram positive bacteria. | ||
| M5930 | Rifampicin | DNA/RNA Synthesis |
| NSC-113926; Rimactane; Rifamycin; Rifadin; Rifater | ||
| Rifampin is a DNA-dependent RNA polymerase inhibitor, it is also a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. | ||
| M6020 | Tobramycin | Antibiotic |
| Nebramycin Factor 6; Deoxykanamycin B | ||
| Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. | ||
| M6289 | Erythromycin cyclocarbonate | Antibiotic |
| Erythromycin cyclic carbonate; Erythromycin A 11,12-carbonate | ||
| Erythromycin Cyclocarbonate, derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome. | ||
| M7015 | Nanchangmycin | Others |
| Nanchangmycin A | ||
| Nanchangmycin is an antiviral compound; Has a positive effect on Zika, West Nile and Dengue. | ||
| M7419 | Toyocamycin | Apoptosis |
| Vengicide | ||
| Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin is a adenosine analog; antifungal antibiotic. | ||
| M7720 | Caerulomycin A | Others |
| Cerulomycin; CRM A; CaeA | ||
| Caerulomycins produced by Streptomyces caeruleus are bipyridinic molecules endowed with antibiotic properties. | ||
| M7721 | Chrysomycin B | Others |
| Antibiotic from Streptomyces sp. | ||
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