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Pentostatin (Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase (Ki = 2.5 pM). Pentostatin (Deoxycoformycin) is useful for anticancer agent. Pentostatin is of limited benefit in the treatment for SR grade III-IV aGVHD.
| Molecular Weight | 268.27 |
| Formula | C11H16N4O4 |
| CAS Number | 53910-25-1 |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Klohs WD, et al. Pharmacol Rev. Pentostatin: future directions.
| Related Adenosine Deaminase Products |
|---|
| AMPD2 inhibitor 1
AMPD2 inhibitor 1 is an adenosine monophosphate deaminase 2 (AMPD2) inhibitor, used in the research of sugar craving, salt craving, umami craving, and addictions including agent, tobacco, nicotine and alcohol addictions. |
| Rebecsinib
Rebecsinib, an RNA adenosine deaminase (ADAR) inhibitor, reverses malignant over-editing by inhibiting ADAR1 p150-driven self-renewal of leukemic stem cells. |
| FR221647
FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase. |
| Hibifolin
Hibifolin, a flavonol glycoside, is a potential inhibitor of adenosine deaminase (ADA), with a Ki of 49.92 μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity. |
| ABT-702 dihydrochloride
ABT-702 dihydrochloride is a potent non-nucleoside adenosine kinase inhibitor, selective over other sites of adenosine interaction like A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase. |
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