All AbMole products are for research use only, cannot be used for human consumption.
Calcimycin (A-23187), a calcium ionophore, is used to induce Ca(2+)-dependent cell death by increasing intracellular Ca(2+) concentration ([Ca(2+)](i)) under in vitro condition. Calcimycin (A-23187) promotes intracelllular ROS generation and platelet particle formation (fragmentation) in vitro and in vivo. Calcimycin (A-23187) induced trace Zn(2+), derived from cell preparation, partly attenuates the Ca(2+)-dependent cell death. Calcimycin (A-23187) can be used to induce autophagy in mammalian cells.
| Molecular Weight | 523.63 |
| Formula | C29H37N3O6 |
| CAS Number | 52665-69-7 |
| Solubility (25°C) | DMSO 27 mg/mL |
| Storage | 4°C, dry, sealed |
| Related CaMK Products |
|---|
| Autocamtide 2
Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). |
| Syntide 2
Syntide 2, a Ca2+- and calmodulin (CaM)-dependent protein kinase II (CaMKII) substrate peptide, selectively inhibits the gibberellin (GA) response, leaving constitutive and abscisic acid-regulated events unaffected. |
| Autocamtide-2-related inhibitory peptide, myristoylated
Autocamtide-2-related inhibitory peptide, myristoylated is the myristoylated Autocamtide-2-related inhibitory peptide. |
| Calmodulin Dependent Protein Kinase Substrate
Calmodulin Dependent Protein Kinase Substrate is a Ca2+- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. |
| Calmodulin Dependent Protein Kinase Substrate Analog
Calmodulin Dependent Protein Kinase Substrate Analog is a Ca2+- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
