About 27 results found for searched term "CaMK" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14557 | CaMKII-IN-1 | CaMK |
| CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM; significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC. | ||
| M41594 | CaMKP inhibitor sodium | ROCK |
| CaMKP inhibitor sodium is a selective inhibitor of ROCK1 with an IC50 value of 14 nM. | ||
| M52414 | CaMKII inhibitory peptide KIIN | CaMK |
| CaMKII inhibitory peptide KIIN is a potent inhibitor of CaMKII. | ||
| M1928 | KN-62 | CaMK |
| KN-62 is a selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II (CaMKII; IC50 = 900 nM). | ||
| M2879 | NH125 | CaMK |
| NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor. | ||
| M5303 | 1-Naphthyl PP1 | PKC |
| 1-NA-PP 1 | ||
| 1-Naphthyl PP1(1-NA-PP 1) is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). | ||
| M6649 | CZC-25146 | LRRK2 |
| CZC25146 | ||
| CZC 25146 is a potent and orally active LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well. | ||
| M9266 | STO-609 acetate | CaMK |
| STO609 | ||
| STO-609 acetate is a cell-permeable inhibitor of calcium/calmodulin-dependent kinase kinases (CaMKK) isoforms CaMKKα and CaMKKβ with Ki of 80 and 15 ng/ml, respectively. | ||
| M9624 | KN-93 hydrochloride | CaMK |
| KN-93 HCl | ||
| KN-93 hydrochloride is a cell-permeable inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMK-II) with a Ki of 370 nM. | ||
| M14556 | Autocamtide-2-related inhibitory peptide TFA | CaMK |
| Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. | ||
| M14559 | Syntide 2 TFA | CaMK |
| Syntide 2 (TFA), a Ca2+- and calmodulin (CaM)-dependent protein kinase II (CaMKII) substrate peptide, selectively inhibits the gibberellin (GA) response, leaving constitutive and abscisic acid-regulated events unaffected. | ||
| M14909 | 1-Naphthyl PP1 hydrochloride | Src-bcr-Abl |
| 1-NA-PP 1 hydrochloride | ||
| 1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases. 1-Naphthyl PP1 hydrochloride inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively. | ||
| M21332 | Calmidazolium chloride | CaMK |
| R 24571 | ||
| Calmidazolium chloride (R 24571) is a calmodulin antagonist that antagonizes CaM-dependent phosphodiesterase and calmodulin-induced activation of Ca2+-transporting ATPase in erythrocytes with IC50s of 0.15 and 0.35 μM, respectively. it is also used in anticancer studies. It binds CaMK with a Kd value of 3 nM. | ||
| M28067 | Lavendustin C | CaMK |
| Lavendustin C is a potent Ca2+ calmodulin-dependent kinase II (CaMK II) inhibitor with an IC50 of 0.2 µM. Lavendustin C inhibits EGFR-associated tyrosine kinase (IC50=0.012 µM) and pp60c-src(+) kinase (IC50=0.5 µM) . | ||
| M29106 | NYX-2925 | GluR |
| NYX-2925 is an orally active NMDAR modulator. NYX-2925 restores levels of activated Src and Src phosphorylation sites on GluN2A and GluN2B in the mPFC. NYX-2925 shows no effect on CAMKII, and any addictive or sedative/ataxic side effects. NYX-2925 can be used for research of a variety of NMDA receptor-mediated central nervous system disorders. | ||
| M29547 | Ph-HTBA | CaMK |
| Ph-HTBA is a high-affinity, brain-penetrating modulator for CaMKIIα. Ph-HTBA has binding affinity for CaMKIIα with a Kd value of 757 nM. Ph-HTBA can be used for the research of ischemia and neurodegenerative disorders. | ||
| M29821 | HS-276 | IRAK |
| HS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 can be used for rheumatoid arthritis (RA) research. | ||
| M31204 | RSVA405 | AMPK |
| RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function. | ||
| M42635 | Autocamtide-3 acetate | CaMK |
| Autocamtide-3 acetate, a 13-amino-acid peptide containing Thr287, is a selective CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK) substrate. | ||
| M42636 | CS587 | CaMK |
| CS587 is a specific inhibitor of CaMK1D with neurocytotoxicity at 10 μM. | ||
| M52413 | Autocamtide-3 | CaMK |
| Autocamtide-3, a 13-amino-acid peptide containing Thr287, is a selective CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK) substrate. | ||
| M52415 | Autocamtide-2-related inhibitory peptide | CaMK |
| Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. | ||
| M52416 | Calmodulin Dependent Protein Kinase Substrate Analog | CaMK |
| Calmodulin Dependent Protein Kinase Substrate Analog is a Ca2+- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. | ||
| M52417 | Calmodulin Dependent Protein Kinase Substrate | CaMK |
| Calmodulin Dependent Protein Kinase Substrate is a Ca2+- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. | ||
| M52419 | Syntide 2 | CaMK |
| Syntide 2, a Ca2+- and calmodulin (CaM)-dependent protein kinase II (CaMKII) substrate peptide, selectively inhibits the gibberellin (GA) response, leaving constitutive and abscisic acid-regulated events unaffected. | ||
| M53364 | Calmodulin-Dependent Protein Kinase II (290-309) | Autophagy |
| Calmodulin-Dependent Protein Kinase II (290-309) is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II. | ||
| M54001 | Autocamtide 2 | CaMK |
| Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). | ||
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