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Capreomycin Sulfate

Cat. No. M2488
Capreomycin Sulfate Structure
Size Price Availability Quantity
250mg USD 75  USD75 In stock
500mg USD 105  USD105 In stock
1g USD 174  USD174 In stock
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Quality Control & Documentation
Biological Activity

Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit.

Chemical Information
Molecular Weight 750.78
Formula C25H44N14O7.H2SO4
CAS Number 1405-37-4
Form Solid
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] No authors listed. Capreomycin

[2] No authors listed. Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis

[3] Guozhu Liu, et al. Isolation and identification of four major impurities in capreomycin sulfate

[4] No authors listed. Capreomycin

[5] No authors listed. Tuberculosis (Edinb). Capreomycin

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Keywords: Capreomycin Sulfate supplier, Antibiotic, inhibitors, activators

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