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Marbofloxacin

Cat. No. M1870

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Marbofloxacin Structure
Size Price Availability Quantity
200mg USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Marbofloxacin is a quinolone, and acts by inhibiting bacterial DNA replication. It is effective against enterobacteria, Pasteurella, Pseudomonas and staphylococci. Marbofloxacin has demonstrated considerable pharmokinetic variation among avian species. Marbofloxacin significantly kills Leishmania promastigotes and intracellular amastigotes in a dose-dependent manner, more efficient than meglumine antimoniate and sodium stibogluconate. Clearance and V(d(ss)) for marbofloxacin was 4.62 +/- 0.67 mL/min/kg and 1.6 +/- 0.25 L/kg. Variance of the AUC(0-inf) of marbofloxacin was low, with a CV = 15% and a CV = 31% after oral administration.

Chemical Information
Molecular Weight 362.36
Formula C17H19FN4O4
CAS Number 115550-35-1
Form Solid
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bouassiba et al. Tierarztl Prax Ausg K Kleintiere Heimtiere. In-vivo efficacy of a commercial ear antiseptic containing chlorhexidine and Tris-EDTA. A randomised, placebo-controlled, double-blinded comparative trial.

[2] Garcia-Montijano et al. J Avian Med Surg. Marbofloxacin disposition after intravenous administration of a single dose in wild mallard ducks (Anas platyrhynchos).

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