All AbMole products are for research use only, cannot be used for human consumption.
Tunicamycin inhibits GlcNAc phosphotransferase (GPT).Tunicamycin blocks the formation of N-glycosidic linkages by inhibiting the first step in glycoprotein synthesis.Tunicamycin can be used to induce autophagy.Tunicamycin induces apoptosis in association with caspase-3 activation, generation of reactive oxygen species (ROS), and downregulation of survivin expression.P38 MAPK (mitogen-activated protein kinase) and the generation of ROS signaling pathway play crucial roles in TN-induced apoptosis in U937 cells.TN modulates multiple components of the apoptotic response of human leukemia cells and raise the possibility of a novel therapeutic strategy for hematological malignancies.
Int J Surg. 2024 Dec 20.
Loss of RPN1 Promotes Antitumor Immunity via PD-L1 Checkpoint Blockade in Triple-negative Breast Cancer——Experimental Studies
Tunicamycin purchased from AbMole
Ecotoxicol Environ Saf. 2024 Jul 13.
ATF4-mediated different mode of interaction between autophagy and mTOR determines cell fate dependent on the level of ER stress induced by Cr(VI)
Tunicamycin purchased from AbMole
Toxicology. 2024 Jul 19.
HMGA2-mediated glutamine metabolism is required for Cd-induced cell growth and cell migration
Tunicamycin purchased from AbMole
Toxicology. 2024 Oct 18.
ATF4/PHGDH mediates the effects of ER stress on cadmium-induced autophagy and glycolysis
Tunicamycin purchased from AbMole
Tissue Cell. 2024 Aug 23;91:102531.
BRD4 absence inactivates endoplasmic reticulum stress to retard dehydroepiandrosterone-triggered ovarian granular cell apoptosis in polycystic ovary syndrome via GRP78
Tunicamycin purchased from AbMole
Stem Cells Int. 2023 Jul 26;2023:4483776.
Mesenchymal Stem Cells Inhibit Epithelial-to-Mesenchymal Transition by Modulating the IRE1α Branch of the Endoplasmic Reticulum Stress Response
Tunicamycin purchased from AbMole
Tissue Cell. 2023 Jul 26;84:102183.
Krüppel-like factor 15 counteracts endoplasmic reticulum stress and suppresses lung fibroblast proliferation and extracellular matrix accumulation
Tunicamycin purchased from AbMole
J Ethnopharmacol. 2022 October 5;296:115519.
Lycium barbarum L. and Salvia miltiorrhiza Bunge protect retinal pigment epithelial cells through endoplasmic reticulum stress
Tunicamycin purchased from AbMole
Research Square. 2022 Apr 13.
Mesenchymal stem cells alleviate epithelial-to-mesenchymal transition by modulating the IRE1α branch of the endoplasmic reticulum stress response
Tunicamycin purchased from AbMole
Molecular Weight | 816.89 |
Formula | C37H60N4O16 |
CAS Number | 11089-65-9 |
Solubility (25°C) | DMSO 30 mg/mL |
Storage | -20°C, protect from light, dry, sealed |
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Products are for research use only. Not for human use. We do not sell to patients.
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