|M10279||Ibiglustat||Ibiglustat (Venglustat) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor.|
|M10176||3-Methoxybenzamide||3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase with Ki values of less than 2 μM and also inhibits ADP-ribosyltransferase (ADPRT).|
|M10100||Opicapone||Opicapone, also known as BIA 9-1067, is a novel potent and selective catechol-O-methyltransferase inhibitor (COMT inhibitor).|
|M9349||Adenosine Dialdehyde||Adenosine Dialdehyde (ADOX) is an adenosine analog and S-adenosylmethionine-dependent methyltransferase inhibitor with an IC50 of 40 nM.|
|M9234||Hecogenin||Hecogenin is a potent and highly selective inhibitor of UGT1A4 with an IC50 value of 1.5 μM.|
|M4798||Tunicamycin||Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes.|
|M3078||Tolcapone||Tolcapone is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM.|
|M2926||PF-04620110||PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.|
|M2804||LB42708||LB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively.|
|M2722||AZD7687||GlcNAcstatin inhibits a bacterial O-GlcNAcase (bOGA) with a Ki of 4.6 pM, inhibits human O-GlcNAcase (hOGA) with Ki of 4.4 nM, exhibits 164-fold selectivity over HexA/B.|
|M2307||Lonafarnib||Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.|
|M2287||APO866||APO866 effectively inhibits NAMPT with IC50 of 0.09 nM.|
|M2059||A-922500||A-922500 is a potent and selective DGAT-1 inhibitor with IC50 values of 7 and 24 nM at human and mouse DGAT-1 respectively.|
|M1885||Tipifarnib||Tipifarnib (R115777) is an oral farnesyltransferase inhibitor with activity in AML.|
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