All AbMole products are for research use only, cannot be used for human consumption.
SHIN1 (RZ-2994) is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor with IC50s of 5 and 13 nM, respectively, in an in vitro assay.
| Molecular Weight | 400.47 |
| Formula | C24H24N4O2 |
| CAS Number | 2146095-85-2 |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Shinichi Mizuno, et al. Amyloid cast nephropathy with systemic AL amyloidosis
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