About 30 results found for searched term "FAS" (0.038 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1872 | Fasudil hydrochloride | ROCK |
| HA-1077; AT877 | ||
| Fasudil hydrochloride is a potent Rho-associated kinase inhibitor with IC50 of 10.7 μM. | ||
| M2054 | Fasiglifam (TAK-875) Hemihydrate | GPR/FFAR |
| Fasiglifam Hemihydrate; TAK875 hydrate | ||
| Fasiglifam (TAK-875) Hemihydrate is a novel, orally available, selective GPR40 agonist. | ||
| M2197 | Sulfasalazine | Ferroptosis |
| Salazopyrin; Azulfidine; Sulphasalazine; SAS; NSC 667219 | ||
| Sulfasalazine is a sulfonamide agent derived from Mesalazine. Sulfasalazine has xC-system inhibitory activity associated with iron death and is primarily used as an anti-inflammatory agent. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer. | ||
| M3607 | Fasudil | ROCK |
| AT-877; HA-1077 | ||
| Fasudil (HA-1077) is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively. | ||
| M5260 | Hydroxyfasudil hydrochloride | ROCK |
| HA-1100 HCl | ||
| Hydroxyfasudil (HA-1100), an active metabolite of fasudil hydrochloride, is a specific Rho-kinase(ROCK) inhibitor with IC50 values of 0.73 μM and 0.72 μM for ROCK1 and ROCK2, respectively. | ||
| M7805 | Fasentin | Others |
| Fasentin is a novel inhibitor of glucose uptake, GluT1 inhibitor. | ||
| M10300 | Thymosin alpha 1 | Peptides |
| Thymosin α1; Thymalfasin | ||
| Thymalfasin is an immunomodulatory compound that enhances the immune response of Thl. Sequence: N-acetyl-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Glu-Glu-Glu-Ala-Glu-Asn. | ||
| M10746 | Denifanstat | FAS |
| TVB-2640; FASN-IN-2; ASC-40 | ||
| Denifanstat (TVB-2640) is an orally potent selective FASN inhibitor.IC50 to 0.052 μM,EC50 is 0.072 μM. Denifanstat has the potential to be used in fatty liver and cancer research. | ||
| M11156 | Nuclear fast red | Fluorescent Dye |
| Nuclear Fast Red, an anthraquinone dye, is commonly used in conjunction with an excess of aluminum ions as a red nuclear counterstain. Light purple on sodium hydroxide, brown in sulfuric acid solution. Soluble in ethanol and water. Maximum absorption wavelength 518nm. Irritating. It can be used for nucleus staining of connective tissue and determination of calcium in serum. | ||
| M13728 | Hydroxyfasudil | ROCK |
| HA-1100 | ||
| Hydroxyfasudil is a ROCK inhibitor, with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively. | ||
| M13783 | Fast-TRFS | Fluorescent Dye |
| Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells. | ||
| M13962 | Fasiglifam | FAS |
| TAK-875 | ||
| Fasiglifam (TAK-875) is a potent, selective and orally bioavailable GPR40 agonist with EC50 of 72 nM. | ||
| M14432 | FASN-IN-4 tosylate | FAS |
| FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 tosylate also inhibits SARS-CoV-2 with an EC50 of 18.6 nM. | ||
| M14433 | FASN-IN-1 | FAS |
| FASN-IN-1 is a fatty acid synthase (FASN) inhibitor. | ||
| M21161 | Thymalfasin | Peptides |
| Thymosin α1; Thymosin alpha 1 | ||
| Thymalfasin is an immunomodulatory compound that enhances the immune response of Thl. Sequence: N-acetyl-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Glu-Glu-Glu-Ala-Glu-Asn. | ||
| M22360 | FAS-IN-1 | Others |
| FAS-IN-1 | ||
| M22373 | Fascaplysin chloride | Others |
| Fascaplysin chloride | ||
| M24572 | Fasinumab | Others |
| Fasinumab (Anti-Human NGF) is a human IgG1k monoclonal antibody to nerve growth factor (NGF). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies. | ||
| M24646 | Lifastuzumab vedotin | Drug-Linker Conjugates for ADC |
| DNIB0600A | ||
| Lifastuzumab vedotin (DNIB0600A) is an antibody-drug conjugate (ADC) that comprises a humanized IgG1 anti-NaPi2b monoclonal antibody (MNIB2126A) and a potent antimitotic agent, monomethyl auristatin E (MMAE), which inhibits cell division by blocking the polymerization of tubulin. | ||
| M24666 | Tafasitamab | Apoptosis |
| XmAb5574; MOR00208; zz-cxix | ||
| Tafasitamab (XmAb5574) is an Fc-modified, humanized monoclonal antibody that binds to the human B-cell surface antigenCD19. | ||
| M24724 | Afasevikumab | IL Receptor/Related |
| RG 7624; RO 5553110; NI-1401 | ||
| Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities. | ||
| M25274 | Elosulfase alfa | Others |
| BMN 110; Chondrosulfatase Chondroitinase Chondrosulfatases Chondroitin sulfatase | ||
| Elosulfase alfa (BMN 110) is a recombinant form of human N-acetylgalactosamine-6-sulfatase (GALNS). Elosulfase alfa is used as an enzyme replacement therapy for mucopolysaccharidosis IVA (MPS IVA), also known as Morquio A syndrome. | ||
| M27594 | Rifasutenizol | Antibiotic |
| TNP-2198 | ||
| Rifasutenizol (TNP-2198) is a potent and orally bioavailable dual-targeted antibacterial agent. Rifasutenizol has potent activity against microaerophilic and anaerobic bacterial pathogens. | ||
| M27862 | Fasitibant chloride | Bradykinin Receptor |
| MEN16132 free base | ||
| Fasitibant chloride (MEN16132 free base) is a potent and selective nonpeptide bradykinin B2 receptor (B2R) antagonist. Fasitibant chloride reduces joint pain and diminishes joint oedema in Carrageenan-induced arthritis rat model. | ||
| M28999 | Onfasprodil | GluR |
| Onfasprodil is negative allosteric modulator of NR2B. Onfasprodil in combination with GABA receptor regulator has the potential for the research of Alzheimer's disease (extracted from patent CN111481543A). | ||
| M29494 | Fasedienol | GABA Receptor |
| PH94B | ||
| Fasedienol is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol alleviates the symptoms of PMS and anxiety. | ||
| M30761 | Fasitibant chloride hydrochloride | Bradykinin Receptor |
| MEN16132 | ||
| Fasitibant chloride hydrochloride (MEN16132) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant chloride hydrochloride has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis. | ||
| M30763 | Fasitibant free base | Bradykinin Receptor |
| Fasitibant (free base) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant (free base) has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis. | ||
| M40623 | Fasudil mesylate | ROCK |
| Fasudil mesylate is a potent inhibitor of ROCKs with neuroprotective activity for studies related to cerebral infarction. | ||
| M45267 | Recombinant Mouse Fas/CD95 Protein (HEK293, C-6His) | Cytokines and Growth Factors |
| Apoptosis-mediating surface antigen FAS; TNFRSF6 | ||
| Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. | ||
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