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 About 30 results found for searched term "FAS" (0.064 seconds)

Cat.No.  Name Target
M1872 Fasudil hydrochloride ROCK
HA-1077; AT877
Fasudil hydrochloride is a potent Rho-associated kinase inhibitor with IC50 of 10.7 μM.
M2054 Fasiglifam (TAK-875) Hemihydrate GPR/FFAR
Fasiglifam Hemihydrate; TAK875 hydrate
Fasiglifam (TAK-875) Hemihydrate is a novel, orally available, selective GPR40 agonist.
M2197 Sulfasalazine Ferroptosis
Salazopyrin;Azulfidine;Sulphasalazine; SAS
Sulfasalazine is a sulfonamide agent derived from Mesalazine. Sulfasalazine has xC-system inhibitory activity associated with iron death and is primarily used as an anti-inflammatory agent.
M3607 Fasudil ROCK
AT-877
Fasudil (HA-1077) is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively.
M5260 Hydroxyfasudil hydrochloride ROCK
HA-1100 HCl
Hydroxyfasudil (HA-1100), an active metabolite of fasudil hydrochloride, is a specific Rho-kinase(ROCK) inhibitor with IC50 values of 0.73 μM and 0.72 μM for ROCK1 and ROCK2, respectively.
M7805 Fasentin Others
Fasentin is a novel inhibitor of glucose uptake, GluT1 inhibitor.
M10300 Thymosin alpha 1 Peptides
Thymosin α1; Thymalfasin
Thymosin alpha 1 (Thymalfasin) is an immunomodulating agent able to enhance the Thl immune response.
M10746 Denifanstat FAS
TVB-2640; FASN-IN-2; ASC-40
Denifanstat (TVB-2640) is an orally potent selective FASN inhibitor.IC50 to 0.052 μM,EC50 is 0.072 μM. Denifanstat has the potential to be used in fatty liver and cancer research.
M11156 Nuclear fast red Fluorescent Dye
细胞核坚牢红;钙红;核快红;乙二醛缩双邻氮基酚
Light purple on sodium hydroxide, brown in sulfuric acid solution. Soluble in ethanol and water. Maximum absorption wavelength 518nm. Irritating. It can be used for nucleus staining of connective tissue and determination of calcium in serum.
M13728 Hydroxyfasudil ROCK
HA-1100
Hydroxyfasudil is a ROCK inhibitor, with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively.
M13783 Fast-TRFS Fluorescent Dye
Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells.
M13962 Fasiglifam FAS
TAK-875
Fasiglifam (TAK-875) is a potent, selective and orally bioavailable GPR40 agonist with EC50 of 72 nM.
M14432 FASN-IN-4 tosylate FAS
FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 tosylate also inhibits SARS-CoV-2 with an EC50 of 18.6 nM.
M14433 FASN-IN-1 FAS
FASN-IN-1 is a fatty acid synthase (FASN) inhibitor.
M21161 Thymalfasin Peptides
Thymalfasin is an immunomodulatory compound that enhances the immune response of Thl. Sequence: N-acetyl-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Glu-Glu-Glu-Ala-Glu-Asn.
M22360 FAS-IN-1 Others
FAS-IN-1
M22373 Fascaplysin chloride Others
Fascaplysin chloride
M24572 Fasinumab Others
Fasinumab (Anti-Human NGF) is a human IgG1k monoclonal antibody to nerve growth factor (NGF). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies.
M24646 Lifastuzumab vedotin Drug-Linker Conjugates for ADC
DNIB0600A
Lifastuzumab vedotin (DNIB0600A) is an antibody-drug conjugate (ADC) that comprises a humanized IgG1 anti-NaPi2b monoclonal antibody (MNIB2126A) and a potent antimitotic agent, monomethyl auristatin E (MMAE), which inhibits cell division by blocking the polymerization of tubulin.
M24666 Tafasitamab Apoptosis
XmAb5574; MOR00208; zz-cxix
Tafasitamab (XmAb5574) is an Fc-modified, humanized monoclonal antibody that binds to the human B-cell surface antigenCD19.
M24724 Afasevikumab IL Receptor/Related
RG 7624; RO 5553110; NI-1401
Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities.
M25274 Elosulfase alfa Others
BMN 110; Chondrosulfatase Chondroitinase Chondrosulfatases Chondroitin sulfatase
Elosulfase alfa (BMN 110) is a recombinant form of human N-acetylgalactosamine-6-sulfatase (GALNS). Elosulfase alfa is used as an enzyme replacement therapy for mucopolysaccharidosis IVA (MPS IVA), also known as Morquio A syndrome.
M27594 Rifasutenizol Antibiotic
TNP-2198
Rifasutenizol (TNP-2198) is a potent and orally bioavailable dual-targeted antibacterial agent. Rifasutenizol has potent activity against microaerophilic and anaerobic bacterial pathogens.
M27862 Fasitibant chloride Bradykinin Receptor
MEN16132 free base
Fasitibant chloride (MEN16132 free base) is a potent and selective nonpeptide bradykinin B2 receptor (B2R) antagonist. Fasitibant chloride reduces joint pain and diminishes joint oedema in Carrageenan-induced arthritis rat model.
M28999 Onfasprodil  GluR
Onfasprodil is negative allosteric modulator of NR2B. Onfasprodil in combination with GABA receptor regulator has the potential for the research of Alzheimer's disease (extracted from patent CN111481543A).
M29494 Fasedienol GABA Receptor
PH94B
Fasedienol is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol alleviates the symptoms of PMS and anxiety.
M30761 Fasitibant chloride hydrochloride Bradykinin Receptor
MEN16132
Fasitibant chloride hydrochloride (MEN16132) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant chloride hydrochloride has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis.
M30763 Fasitibant free base  Bradykinin Receptor
Fasitibant (free base) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant (free base) has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis.
M40623 Fasudil mesylate ROCK
Fasudil mesylate is a potent inhibitor of ROCKs with neuroprotective activity for studies related to cerebral infarction.
M45267 Recombinant Mouse Fas/CD95 Protein (Mammalian, C-6His) Recombinant Proteins
Apoptosis-mediating surface antigen FAS; TNFRSF6
Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.



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