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Sulfasalazine

Cat. No. M2197

All AbMole products are for research use only, cannot be used for human consumption.

Sulfasalazine Structure
Synonym:

Salazopyrin; Azulfidine; Sulphasalazine; SAS; NSC 667219

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
100mg USD 30  USD30 In stock
500mg USD 40  USD40 In stock
1g USD 50  USD50 In stock
5g USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Sulfasalazine is a sulfonamide agent derived from Mesalazine. Sulfasalazine has xC-system inhibitory activity associated with iron death and is primarily used as an anti-inflammatory agent. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer.

Chemical Information
Molecular Weight 398.39
Formula C18H14N4O5S
CAS Number 599-79-1
Solubility (25°C) DMSO 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Liang Wang, et al. Front Pharmacol. Arbutin Ameliorates Murine Colitis by Inhibiting JAK2 Signaling Pathway

[2] Fereshteh Asgharzadeh, et al. EXCLI J. The beneficial effect of combination therapy with sulfasalazine and valsartan in the treatment of ulcerative colitis

[3] Young-Jae Hwang, et al. PLoS One. Anti-inflammatory effects of apocynin on dextran sulfate sodium-induced mouse colitis model

[4] Yanrong Liu, et al. J Cell Mol Med. Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer

[5] Helieh S Oz, et al. Front Immunol. Green Tea Polyphenols and Sulfasalazine have Parallel Anti-Inflammatory Properties in Colitis Models

[6] Lo M, et al. Curr Oncol. Potential use of the anti-inflammatory drug, sulfasalazine, for targeted therapy of pancreatic cancer.

[7] Robe PA, et al. Clin Cancer Res. In vitro and in vivo activity of the nuclear factor-kappaB inhibitor sulfasalazine in human glioblastomas.

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Keywords: Sulfasalazine, Salazopyrin; Azulfidine; Sulphasalazine; SAS; NSC 667219 supplier, Ferroptosis, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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