All AbMole products are for research use only, cannot be used for human consumption.
Denifanstat (TVB-2640) is an orally potent selective FASN inhibitor.IC50 to 0.052 μM,EC50 is 0.072 μM. Denifanstat has the potential to be used in fatty liver and cancer research.
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Animal models | female C57/BL6 mice |
Formulation | formulated in 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline |
Dosages | 25 mg/kg |
Administration | daily gavage |
Molecular Weight | 439.55 |
Formula | C27H29N5O |
CAS Number | 1399177-37-7 |
Solubility (25°C) | DMSO 90 mg/mL |
Storage | 4°C, protect from light |
Related FAS Products |
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Fasnall
Fasnall is a selective fatty acid synthase (FASN) inhibitor with an IC50 of 3.71 μM. |
Fasnall benzenesulfonate
Fasnall benzenesulfonate is the benzenesulfonate salt form of Fasnall. |
GSK837149A
GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (Ki=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer. |
IPI-9119
IPI-9119 is an orally active, selective and irreversible Fatty Acid Synthase (FASN) inhibitor, with an IC50 of 0.3 nM. |
Eicosapentaenoic acid ethyl ester
Eicosapentaenoic acid ethyl ester (AMR101, EPA ethyl ester, Ethyl eicosapentaenoate) is an omega-3 fatty acid agent that significantly reduces the triglyceride (TG) levels and improves other lipid parameters without significantly increasing the low-density lipoprotein (LDL) cholesterol levels. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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