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Denifanstat

Cat. No. M10746

All AbMole products are for research use only, cannot be used for human consumption.

Denifanstat Structure
Synonym:

TVB-2640; FASN-IN-2; ASC-40

Size Price Availability Quantity
1mg USD 85  USD85 In stock
5mg USD 215  USD215 In stock
10mg USD 350  USD350 In stock
25mg USD 580  USD580 In stock
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Quality Control & Documentation
Biological Activity

Denifanstat (TVB-2640) is an orally potent selective FASN inhibitor.IC50 to 0.052 μM,EC50 is 0.072 μM. Denifanstat has the potential to be used in fatty liver and cancer research.

Protocol (for reference only)
Cell Experiment
Cell lines
Preparation method
Concentrations
Incubation time
Animal Experiment
Animal models female C57/BL6 mice
Formulation formulated in 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline
Dosages 25 mg/kg
Administration daily gavage
Chemical Information
Molecular Weight 439.55
Formula C27H29N5O
CAS Number 1399177-37-7
Solubility (25°C) DMSO 90 mg/mL
Storage 4°C, protect from light
References

[1] Jiao Huang, et al. Cancer Res. FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma

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  Catalog
Abmole Inhibitor Catalog




Keywords: Denifanstat, TVB-2640; FASN-IN-2; ASC-40 supplier, FAS, inhibitors, activators

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