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Recombinant Mouse Fas/CD95 Protein (HEK293, C-6His)

Cat. No. M45267

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse Fas/CD95 Protein (HEK293, C-6His) Structure
Synonym:

Apoptosis-mediating surface antigen FAS; TNFRSF6

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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

Recombinant Mouse FAS expressed the target gene encoding Gln22-Arg169 with a 6His tag at the C-terminus.


Accession: P25446

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 25-35 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Catherine Duez, et al. Arterioscler Thromb Vasc Biol. Regulation of IL (Interleukin)-33 Production in Endothelial Cells via Kinase Activation and Fas/CD95 Upregulation

[2] Arno Reich, et al. J Neurosci. Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemia

[3] Wim J van Blitterswijk, et al. Biochem J. Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency

[4] R G Fenton, et al. Cancer Res. Inhibition of Fas (CD95) expression and Fas-mediated apoptosis by oncogenic Ras

[5] H Cui, et al. Cell Immunol. Functional expression of Fas (CD95) protein in autoimmune lpr mice

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Keywords: Recombinant Mouse Fas/CD95 Protein (HEK293, C-6His), Apoptosis-mediating surface antigen FAS; TNFRSF6 supplier, Cytokines and Growth Factors, inhibitors, activators

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