Free shipping on all orders over $ 500

Fasitibant chloride

Cat. No. M27862

All AbMole products are for research use only, cannot be used for human consumption.

Fasitibant chloride Structure
Synonym:

MEN16132 free base

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.

Quality Control & Documentation
Biological Activity

Fasitibant chloride (MEN16132 free base) is a potent and selective nonpeptide bradykinin B2 receptor (B2R) antagonist. Fasitibant chloride reduces joint pain and diminishes joint oedema in Carrageenan-induced arthritis rat model.

Chemical Information
Molecular Weight 800.23
Formula C36H49Cl3N6O6S
CAS Number 1157852-02-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Rose-Marie Catalioto, et al. Biochem Pharmacol. Enhanced Ca(2+) response and stimulation of prostaglandin release by the bradykinin B2 receptor in human retinal pigment epithelial cells primed with proinflammatory cytokines

[2] Rose-Marie Catalioto, et al. Biochem Pharmacol. Characterization of a novel proinflammatory effect mediated by BK and the kinin B₂ receptor in human preadipocytes

[3] Claudio Valenti, et al. Br J Pharmacol. Fasitibant chloride, a kinin B₂ receptor antagonist, and dexamethasone interact to inhibit carrageenan-induced inflammatory arthritis in rats

[4] Kenneth J Broadley, et al. J Pharmacol Exp Ther. Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity

[5] Cecilia Cialdai, et al. J Pharmacol Exp Ther. Effect of Intra-articular 4-(S)-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido]-tetrahydro-2H-4-pyranylcarbonyl} piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride (MEN16132), a kinin B2 receptor antagoni䲧瘀Ỵ瘁㧀痿羹皘的㸈ܯŘܯð�皚嶁皖Ѐ瑖犨䀹蹞߸ܯð䀸߸彿犩奋犩巫犩鐚߸

Related Bradykinin Receptor Products
[Hyp3]-Bradykinin

[Hyp3]-Bradykinin, naturally occurring peptide hormone, is a bradykinin receptor agonist.
Bradykinin (1-6)

Bradykinin (1-6) is an amino-truncated Bradykinin peptide.
Lys-[Des-Arg9]Bradykinin TFA

Lys-[Des-Arg9]Bradykinin TFA, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a Ki of 0.12 nM, 1.7 nM and 0.23 nM for human, mouse and rabbit B1 receptors, respectively.
Lobradimil

Lobradimil (RMP 7), a synthetic bradykinin analog, is a potent and selective bradykinin B2 receptor agonist (Ki: 0.54 nM).
[Tyr8] Bradykinin

[Tyr8] Bradykinin is a B2 kinin receptor agonist.
  Catalog
Abmole Inhibitor Catalog




Keywords: Fasitibant chloride, MEN16132 free base supplier, Bradykinin Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.