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SSR240612

Cat. No. M7534

All AbMole products are for research use only, cannot be used for human consumption.

SSR240612 Structure
Size Price Availability Quantity
10mg USD 330  USD330 In stock
25mg USD 660  USD660 In stock
50mg USD 1000  USD1000 In stock
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Quality Control & Documentation
Biological Activity

Treatment with the kinin B1 receptor antagonist, SSR240612, provided a protective effect against organ damage by interfering with multiple target functions, including the suppression of B1R-induced inflammation and platelet aggregation.

Protocol (for reference only)
Cell Experiment
Cell lines
Preparation method
Concentrations
Incubation time
Animal Experiment
Animal models C57BL/6J mice
Formulation
Dosages 10 mg/kg
Administration gavage
Chemical Information
Molecular Weight 793.41
Formula C42H53ClN4O7S
CAS Number 464930-42-5
Form Solid
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] El Akoum S, et al. Obes Sci Pract. Impact of pioglitazone and bradykinin type 1 receptor antagonist on type 2 diabetes in high-fat diet-fed C57BL/6J mice.

[2] Tidjane N, et al. Eur J Inflamm. A primary role for kinin B1 receptor in inflammation, organ damage, and lethal thrombosis in a rat model of septic shock in diabetes.

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Keywords: SSR240612 supplier, Bradykinin Receptor, inhibitors, activators

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