Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M11049 | Neriifolin | Neriifolin, a cardiac glycoside that penetrates the central nervous system, is a typeNa, K-ATPase++ of inhibitors. Neriifolin targets beclin 1, inhibits the formation of LC3-associated phagosomes, and improves the development of experimental autoimmune encephalomyelitis (EAE). |
M11046 | Bixin | Bixin (BX) annatoxin isolated from the seeds of Bixa Orellana, a carotenoid with anti-inflammatory, anti-tumor and antioxidant activities. |
M11003 | Benpyrine | Benpyrine is a highly specific orally active TNF-α inhibitor.KD The value is 82.1 μM. Benpyrine binds tightly to TNF-α and blocks its interaction with TNFR1,IC50 The value is 0.109 μM. |
M11000 | Chlorophyllin sodium copper salt | Sodium copper chlorophyllin A is a semi-synthetic mixture of copper sodium salts derived from Chlorophyll. Commonly used as a food additive. |
M10983 | Ligustrazine hydrochloride | Ligustrazine hydrochloride is a natural product. |
M10925 | Dextran (Mw 70000) | Dextran (Mw 70000) has an inhibitory effect on platelet aggregation and coagulation factors, and can replace part of the whole blood during blood transfusion, and is often used as a plasma volume expander (plasma replacement). |
M10904 | Angstrom6 | Angstrom6 (A6 Peptide) is an 8-amino acid peptide derived from single-stranded urokinase plasminogen activator (scuPA) that interferes with the uPA/uPAR cascade and eliminates downstream effects. Angstrom6 binds to CD44 to inhibit migration, invasion and metastasis of tumor cells and regulate CD44-mediated cell signaling. |
M10903 | Cucurbitadienol | Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis. CYP87D18 catalyzed the oxidation of cucurbitadienol at C-11 to produce 11-oxo cucurbitadienol and 11-hydroxy cucurbitadienol. |
M10867 | Obovatol | Obovatol, a biphenyl ether lignan isolated from the leaves of Magnolia obovata Thunb, possesses antioxidant, neuroprotective, anti-inflammatory, anti-thrombotic, and antitumor activities. In addition, Obovatol targets the pan-apoptosis (PANoptosis)-related molecule NLRP3/AIM2. |
M10855 | Mephenytoin | Mephenytoin is an anticonvulsant that is a substrate for CYP2C19 and CYP2B6. |
M10823 | GNF-6231 | GNF-6231 is a strong, selective, oral-capable Porcupine inhibitor capable of blocking the Wnt signaling pathway. |
M10804 | cedazuridine | Cedazuridine has antineoplastic property. |
M10800 | Vanin-1-IN-1 | Vanin-1-IN-1 is an inhibitor of the vanin-1 enzyme. Vanin-1 is a cell surface-associated inositol (GPi) anchored protein that plays an important role in metabolism and inflammation. |
M10797 | BI-9321 trihydrochloride | BI-9321 trihydrochloride is a potent, selective, cell-active NSD3-PWWP1 antagonist,Kd The value is 166 nM. BI-9321 is not valid for NSD2-PWWP1 and NSD3-PWWP2. BI-9321 trihydrochloride specifically disrupts NSD3-PWWP1 interaction with histones in U2OS cells,IC50 1.2 μM. |
M10794 | BEY-1107 | Avotaciclib (BEY1107) is a potent and orally active cyclin dependent kinase 1 (CDK1) inhibitor. |
M10744 | V-9302 | V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells. |
M10630 | GW280264X | GW280264X is an ADAM17 inhibitor. |
M10613 | Vitexin-4-O-glucoside | Vitexin-4''-O-glucoside is a flavonoid derived from the leaves of Crataegus pinnatifida. |
M10547 | 1-Phenyl-2-thiourea | 1-Phenyl-2-thiourea is a useful biochemical for proteomics research. |
M10544 | Tentoxin | Tentoxin is a cyclic tetrapeptide isolated from Alternaria tenuis, acts as a herbicide, causes seedling chlorosis, inhibits cyclic photophosphorylation and functions as an energy transfer inhibitor. |
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