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Actoxumab

Cat. No. M24590

All AbMole products are for research use only, cannot be used for human consumption.

Actoxumab Structure
Synonym:

Anti-C. difficile Toxin A Recombinant Antibody

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Quality Control & Documentation
Biological Activity

Actoxumab (Anti-C. difficile Toxin A Recombinant Antibody) is a antitoxin antibody against C. difficile toxin A by neutralizing TcdA. Actoxumab prevents both the damage to the gut wall and the inflammatory response, which are associated with C. difficile. Actoxumab has synergy effect with Bezlotoxumab targeting TcdB.

Chemical Information
CAS Number 1245634-25-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Paschalis Paschos, et al. Anaerobe. Add-on interventions for the prevention of recurrent Clostridioides Difficile infection: A systematic review and network meta-analysis

[2] Sarah E Madoff, et al. Anaerobe. Prevention of recurrent Clostridioides difficile infection: A systematic review of randomized controlled trials

[3] Stuart Johnson, et al. Clin Infect Dis. Bezlotoxumab

[4] Brunella Posteraro, et al. Expert Opin Biol Ther. Actoxumab + bezlotoxumab combination: what promise for Clostridium difficile treatment?

[5] Mark H Wilcox, et al. N Engl J Med. Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection

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Keywords: Actoxumab, Anti-C. difficile Toxin A Recombinant Antibody supplier, inhibitors, activators

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