Free shipping on all orders over $ 500

Itolizumab

Cat. No. M24551

All AbMole products are for research use only, cannot be used for human consumption.

Itolizumab Structure
Synonym:

Anti-Human CD6 Recombinant Antibody

Size Price Availability Quantity
100ug USD 190  USD190 In stock
1mg USD 330  USD330 In stock
5mg USD 880  USD880 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Itolizumab (Anti-Human CD6 Recombinant Antibody) is a humanized recombinant anti-CD6 monoclonal antibody (MAb) targeting the extracellular SRCR distal domain 1 of CD6. Itolizumab reduces T-cell proliferation and inhibits the production of pro-inflammatory cytokines, such as INF-γ, TNFα and IL-6. Itolizumab can be used in the research of psoriasis, rheumatoid arthritis (RA), COVID-19.

Chemical Information
CAS Number 1116433-11-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] A García-Lledó, et al. Rev Esp Quimioter. Pharmacological treatment of COVID-19: an opinion paper

[2] Subramanian Loganathan, et al. Expert Opin Biol Ther. Itolizumab, an anti-CD6 monoclonal antibody, as a potential treatment for COVID-19 complications

[3] Leelavathy Budamakuntla, et al. Psoriasis (Auckl). Spotlight on itolizumab in the treatment of psoriasis - current perspectives from India

[4] Ankita Srivastava. Indian J Dermatol. Itolizumab in Psoriasis

[5] Sunil Dogra, et al. Expert Opin Biol Ther. Itolizumab, a novel anti-CD6 monoclonal antibody: a safe and efficacious biologic agent for management of psoriasis

Related Products
DSPE-PEG-FA

DSPE-PEG2K-FA is a PEG derivative containing folic acid. DSPE-PEG2K-FA has a targeting effect and can bind to folic acid receptors in cancer cells. DSPE-PEG2K-FA forms micelles/lipid bilayers and can be used in research on targeted drug delivery systems.

Lifastuzumab

Lifastuzumab is a humanized anti-NaPi2b IgG1 monoclonal antibody.

GPVI antagonist 1

GPVI antagonist 1 is a glycoprotein VI (GPVI) platelet receptor antagonist. GPVI antagonist 1 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM.

MPSD TFA

MPSD TFA (MARCKS-ED TFA) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD TFA can sense membrane curvature and recognize phosphatidylserine. MPSD TFA can be utilized as biological probe to study membrane shape and lipid composition.

4-Nitro-2,1,3-benzoselenadiazole

4-Nitro-2,1,3-benzoselenadiazole is a biochemical material that can be used in scientific research.

  Catalog
Abmole Inhibitor Catalog




Keywords: Itolizumab, Anti-Human CD6 Recombinant Antibody supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.