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Itolizumab

Cat. No. M24551

All AbMole products are for research use only, cannot be used for human consumption.

Itolizumab Structure
Synonym:

Anti-Human CD6 Recombinant Antibody

Size Price Availability Quantity
100ug USD 190  USD190 In stock
1mg USD 330  USD330 In stock
5mg USD 880  USD880 In stock
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Quality Control & Documentation
Biological Activity

Itolizumab (Anti-Human CD6 Recombinant Antibody) is a humanized recombinant anti-CD6 monoclonal antibody (MAb) targeting the extracellular SRCR distal domain 1 of CD6. Itolizumab reduces T-cell proliferation and inhibits the production of pro-inflammatory cytokines, such as INF-γ, TNFα and IL-6. Itolizumab can be used in the research of psoriasis, rheumatoid arthritis (RA), COVID-19.

Chemical Information
CAS Number 1116433-11-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] A García-Lledó, et al. Rev Esp Quimioter. Pharmacological treatment of COVID-19: an opinion paper

[2] Subramanian Loganathan, et al. Expert Opin Biol Ther. Itolizumab, an anti-CD6 monoclonal antibody, as a potential treatment for COVID-19 complications

[3] Leelavathy Budamakuntla, et al. Psoriasis (Auckl). Spotlight on itolizumab in the treatment of psoriasis - current perspectives from India

[4] Ankita Srivastava. Indian J Dermatol. Itolizumab in Psoriasis

[5] Sunil Dogra, et al. Expert Opin Biol Ther. Itolizumab, a novel anti-CD6 monoclonal antibody: a safe and efficacious biologic agent for management of psoriasis

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Keywords: Itolizumab, Anti-Human CD6 Recombinant Antibody supplier, inhibitors, activators

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