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PLGA lactide:glycolide (50:50) MW 120000

Cat. No. M22455

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PLGA lactide:glycolide (50:50) MW 120000 Structure
Size Price Availability Quantity
5g USD 350  USD350 In stock
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Quality Control & Documentation
Biological Activity

Poly(D,L-lactide-co-glycolide) is a synthetic amino acid that has been used to deliver macromolecular therapeutics. The transition temperature (Tg) is 45 ~ 55℃ when the molecular weight is above 30,000. When the molecular weight is below 30,000, the transition temperature (Tg) decreases gradually. It is soluble in most organic solvents such as methylene chloride, tetrahydrofuran, ethyl acetate, acetone, chloroform, and hexafluoroispropanol.

Chemical Information
Formula (C3H4O2)x(C2H2O2)y
CAS Number 26780-50-7
Solubility (25°C) Soluble in methylene chloride
tetrahydrofuran
ethyl acetate
acetone
chloroform
Storage -20°C, sealed
References

[1] Wen-Hui Luo, et al. Pharm Res. Activation of Antigen-Specific CD8(+) T Cells by Poly-DL-Lactide/Glycolide (PLGA) Nanoparticle-Primed Gr-1(high) Cells

[2] John Garner, et al. Int J Pharm. A protocol for assay of poly(lactide-co-glycolide) in clinical products

[3] Vinay Saini, et al. Vaccine. Poly(d,l)-lactide-co-glycolide (PLGA) microspheres as immunoadjuvant for Brugia malayi antigens

[4] A Aranda, et al. Toxicol In Vitro. Dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: a quantitative method for oxidative stress assessment of nanoparticle-treated cells

[5] Kumar G Janoria, et al. Int J Pharm. Effect of lactide/glycolide ratio on the in vitro release of ganciclovir and its lipophilic prodrug (GCV-monobutyrate) from PLGA microspheres

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Keywords: PLGA lactide:glycolide (50:50) MW 120000 supplier, inhibitors, activators

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