Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M9815 | Cholestyramine | Cholestyramine is a bile acid binding resin and can inhibit intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol. |
M9809 | N-Lauroylsarcosine sodium salt | N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency. N-Lauroylsarcosine sodium salt has been used as one of the components of the lysing solution in the cornet assay. It has been used for lysing protoplasts in the process of chromosomal DNA isolation form Streptococcus mutans. |
M9778 | Voxelotor | Voxelotor (GBT 440) is a first-in-class, potent polymeric inhibitor of sickle hemoglobin (HbS). Voxelotor (GBT440) binds to the N-terminal a chain of haemoglobin (Hb), increases haemoglobin S (HbS) affinity for oxygen, delays in vitro HbS polymerization and prevents sickling of red blood cells (RBCs). |
M9777 | 4-Nitroimidazole | 4-Nitroimidazole is an intermediate during the synthesis of 1-methyl-2,4,5-trinitro imidazole. |
M9773 | Triacetyl-ganciclovir | Triacetyl-ganciclovir is related to ganciclovir, which may be used for toxicity studies and other analytical studies during commercial production of Ganciclovir. |
M9766 | GNE-1858 | GNE-1858 is a highly potent ATP competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor that mimics the mutant strains HPK1-TSEE and HPK1-SA for wild-type and active strains IC50The s-values are 1.9 nM, 1.9 nM, and 4.5 nM, respectively. |
M9744 | QM385 | QM385 is a potent sepiapterin reductase (SPR) inhibitor with IC50 of 1.49 nM. |
M9735 | ND-646 | ND-646 is an allosteric inhibitor of the ACC enzymes ACC1 and ACC2 with IC50 values of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively. |
M9734 | 4-Nitrophenyl N-acetyl-β-D-glucosaminide | 4-Nitrophenyl N-acetyl-β-D-glucosaminide is a chromogenic substrate for N-acetyl-glucosaminidase. |
M9732 | Gadopentetate dimeglumine | Gadopentetate dimeglumine is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI. |
M9717 | Etosalamide | Etosalamide (also known as Ethosalamide) is an antipyretic and analgesics agent. |
M9716 | AKOS B018304 | AKOS B018304 is a potent inhibitor of chikungunya virus with low micro molar activity. |
M9707 | HAMNO (NSC111847) | HAMNO (NSC111847) is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response. |
M9701 | Diethylenetriaminepentaacetic acid | Diethylenetriaminepentaacetic acid is a diethylenetriaminepentaacetic anhydride, which is a bifunctional chelating agent. |
M9681 | JBSNF-000088 (6-Methoxynicotinamide) | Jbsnf-000088 (6-methoxynicotinamide) is a niacinamide (NA) analogue, which is a potent NNMT inhibitor. Jbsnf-000088 (6-methoxynicotinamide) is a niacinamide n-methyl transferase (NNMT) inhibitor. The IC50 of monkey NNMT and mouse NNMT were 1.8 µM, 2.8 µM and 5.0 µM, respectively. In animal models of metabolic diseases, JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization and regulates glucose. |
M9680 | 3-Bromopyruvate (3-Bromopyruvic acid) | 3-Bromopyruvate (3-Bromopyruvic acid) is a hexokinase II inhibitor, which is an effective antitumor agent on the hepatoma cells. |
M9670 | (±)-1-(9-Fluorenyl)ethanol | (±)-1-(9-Fluorenyl)ethanol |
M9662 | 2-(4-Methylpiperazin-1-yl)pyrimidine | 2-(4-Methylpiperazin-1-yl)pyrimidine |
M9661 | MF-438 | MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1. |
M9618 | Saponin | Saponins are a class of chemical compounds of glycosides found in particular abundance in various plant species. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects. |
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