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BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 µM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 µM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration.
| Molecular Weight | 418.7748096 |
| Formula | C16H10ClF3N2O4S |
| CAS Number | 406191-34-2 |
| Solubility (25°C) | DMSO ≥ 200 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
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