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4-Deoxypyridoxine hydrochloride

Cat. No. M21073

All AbMole products are for research use only, cannot be used for human consumption.

4-Deoxypyridoxine hydrochloride Structure
Size Price Availability Quantity
10mg USD 60  USD60 In stock
50mg USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

4-Deoxypyridoxine hydrochloride is a vitamin B6 antimetabolite with several biological activities. It inhibits the transport and reduces the growth of pyridoxine, pyridoxal and pyridoxamine in S. carlsbergensis cells. 4-DPD inhibits sphingosine-1-phosphate (S1P) lyase and reduces apoptosis of alveolar epithelial MLE-12 cells induced by cyclic stretch.

Chemical Information
Molecular Weight 189.64
Formula C8H12ClNO2
CAS Number 148-51-6
Solubility (25°C) DMSO: 10 mg/ml
Storage RT
References

[1] Huong N Vu, et al. J Bacteriol. Genetic Analysis Using Vitamin B6 Antagonist 4-Deoxypyridoxine Uncovers a Connection between Pyridoxal 5'-Phosphate and Coenzyme A Metabolism in Salmonella enterica

[2] Nikita V Shtyrlin, et al. Biomed Res Int. Synthesis and Antibacterial Activity of Quaternary Ammonium 4-Deoxypyridoxine Derivatives

[3] Hakmo Lee, et al. Islets. 4-Deoxypyridoxine improves the viability of isolated pancreatic islets ex vivo

[4] S Fridas, et al. Mol Cell Biochem. 4-Deoxypyridoxine inhibits chronic granuloma formation induced by potassium permanganate in vivo

[5] S P Coburn, et al. J Biol Chem. In vivo metabolism of 4'-deoxypyridoxine in rat and man

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