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4-Deoxypyridoxine hydrochloride is a vitamin B6 antimetabolite with several biological activities. It inhibits the transport and reduces the growth of pyridoxine, pyridoxal and pyridoxamine in S. carlsbergensis cells. 4-DPD inhibits sphingosine-1-phosphate (S1P) lyase and reduces apoptosis of alveolar epithelial MLE-12 cells induced by cyclic stretch.
Molecular Weight | 189.64 |
Formula | C8H12ClNO2 |
CAS Number | 148-51-6 |
Solubility (25°C) | DMSO: 10 mg/ml |
Storage | RT |
[5] S P Coburn, et al. J Biol Chem. In vivo metabolism of 4'-deoxypyridoxine in rat and man
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