| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M11061 | Ladanein | Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radicals DPPH and ABTS +.scavenging activity, it also displays moderate (20-40 microM) activities against K562, K562R (imatinib-resistant), and 697 human leukemia cell lines. |
| M11060 | Olivil monoacetate | Olivil monoacetate exist in thorn tea beauty's wood. |
| M11059 | Ganoderenic acid C | Ganoderenic acid C is a triterpenoid isolated from Ganoderma lingzhi, Ganoderenic acid C is abundant in the early stages of ganoderenic acid C growth. |
| M11057 | Ganoderenic acid A | Ganoderenic acid A is a triterpenoid compound. Ganoderenic acid A is a potent inhibitor of β-glucuronidase (β-glucuronidase). Ganoderenic acid A is protective of CCl4-induced liver damage. |
| M11049 | Neriifolin | Neriifolin, a cardiac glycoside that penetrates the central nervous system, is a typeNa, K-ATPase++ of inhibitors. Neriifolin targets beclin 1, inhibits the formation of LC3-associated phagosomes, and improves the development of experimental autoimmune encephalomyelitis (EAE). |
| M11046 | Bixin | Bixin (BX) annatoxin isolated from the seeds of Bixa Orellana, a carotenoid with anti-inflammatory, anti-tumor and antioxidant activities. |
| M11003 | Benpyrine | Benpyrine is a highly specific orally active TNF-α inhibitor.KD The value is 82.1 μM. Benpyrine binds tightly to TNF-α and blocks its interaction with TNFR1,IC50 The value is 0.109 μM. |
| M11000 | Chlorophyllin sodium copper salt | Sodium copper chlorophyllin A is a semi-synthetic mixture of copper sodium salts derived from Chlorophyll. Commonly used as a food additive. |
| M10983 | Ligustrazine hydrochloride | Ligustrazine hydrochloride is a natural product. |
| M10925 | Dextran (Mw 70000) | Dextran (Mw 70000) has an inhibitory effect on platelet aggregation and coagulation factors, and can replace part of the whole blood during blood transfusion, and is often used as a plasma volume expander (plasma replacement). |
| M10904 | Angstrom6 | Angstrom6 (A6 Peptide) is an 8-amino acid peptide derived from single-stranded urokinase plasminogen activator (scuPA) that interferes with the uPA/uPAR cascade and eliminates downstream effects. Angstrom6 binds to CD44 to inhibit migration, invasion and metastasis of tumor cells and regulate CD44-mediated cell signaling. |
| M10903 | Cucurbitadienol | Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis. CYP87D18 catalyzed the oxidation of cucurbitadienol at C-11 to produce 11-oxo cucurbitadienol and 11-hydroxy cucurbitadienol. |
| M10867 | Obovatol | Obovatol, a biphenyl ether lignan isolated from the leaves of Magnolia obovata Thunb, possesses antioxidant, neuroprotective, anti-inflammatory, anti-thrombotic, and antitumor activities. In addition, Obovatol targets the pan-apoptosis (PANoptosis)-related molecule NLRP3/AIM2. |
| M10855 | Mephenytoin | Mephenytoin is an anticonvulsant that is a substrate for CYP2C19 and CYP2B6. |
| M10823 | GNF-6231 | GNF-6231 is a strong, selective, oral-capable Porcupine inhibitor capable of blocking the Wnt signaling pathway. |
| M10804 | cedazuridine | Cedazuridine has antineoplastic property. |
| M10800 | Vanin-1-IN-1 | Vanin-1-IN-1 is an inhibitor of the vanin-1 enzyme. Vanin-1 is a cell surface-associated inositol (GPi) anchored protein that plays an important role in metabolism and inflammation. |
| M10797 | BI-9321 trihydrochloride | BI-9321 trihydrochloride is a potent, selective, cell-active NSD3-PWWP1 antagonist,Kd The value is 166 nM. BI-9321 is not valid for NSD2-PWWP1 and NSD3-PWWP2. BI-9321 trihydrochloride specifically disrupts NSD3-PWWP1 interaction with histones in U2OS cells,IC50 1.2 μM. |
| M10794 | BEY-1107 | Avotaciclib (BEY1107) is a potent and orally active cyclin dependent kinase 1 (CDK1) inhibitor. |
| M10784 | AT791 | AT791 is a potent oral bioavailable inhibitor of TLR7 and TLR9. AT791 inhibits TLR7 and TLR9 signaling for a variety of human and mouse cell types and inhibits DNA-TLR9 interactions in vitro. |
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