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Ferrous Bisglycinate

Cat. No. M22446
Ferrous Bisglycinate Structure
Size Price Availability Quantity
1g USD 30  USD30 In stock
5g USD 45  USD45 In stock
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Quality Control & Documentation
Biological Activity

Ferrous Bisglycinate

Chemical Information
Molecular Weight 203.96
Formula C4H8FeN2O4
CAS Number 20150-34-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Zhenglin Dong, et al. J Agric Food Chem. Ferrous Bisglycinate Supplementation Modulates Intestinal Antioxidant Capacity via the AMPK/FOXO Pathway and Reconstitutes Gut Microbiota and Bile Acid Profiles in Pigs

[2] Cheng-Yi Hsu, et al. J Chin Med Assoc. Low-dose ferrous bisglycinate chelate supplementation in chronic kidney disease and hemodialysis patients

[3] Akkarach Bumrungpert, et al. Nutrients. Efficacy and Safety of Ferrous Bisglycinate and Folinic Acid in the Control of Iron Deficiency in Pregnant Women: A Randomized, Controlled Trial

[4] Xiaonan Yu, et al. Nutrients. Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells

[5] Nils Milman, et al. J Perinat Med. Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial

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