Akt Protein kinase B

Cat.No.	Name	Information
M1837	MK-2206 2HCl	MK-2206 is a novel allosteric inhibitor of Akt with IC50 values of 8 nM, 12 nM and 65 nM for Akt1, Akt2 and Akt3, respectively.
M3068	TIC10	TIC10 (ONC-201) is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier.
M5167	Calpeptin	Calpeptin is a potent, cell-permeable inhibitor of the Ca²⁺-dependent protease, calpain.
M1823	Perifosine	Perifosine is an orally active Akt inhibitor, the antiproliferative properties of Perifosine with an IC50 of 0.6–8.9 µM.
M2303	Capivasertib (AZD5363)	Capivasertib (AZD5363) is a potentially first-in-class, orally effective pan-AKT inhibitor with strong inhibition against all three AKT isomers (AKT1/2/3) at an IC50 of 3 nM/8 nM/8 nM. It also showed similar inhibitory effect on P70S6K/PKA and low inhibitory activity on ROCK1/2.
M5153	SC79	SC79 is a specific and BBB permeable Akt activator used to enhance Akt activity. SC79 activates Akt in the cytosol and inhibits Akt membrane translocation. SC79 specifically binds to the PH domain of Akt. *The compound is unstable in solutions, freshly prepared is recommended
M22523	Recilisib sodium	Recilisib (ON 01210) sodium is a radioprotectant, which can activate AKT, PI3K activities in cells.
M2132	A-674563	A-674563 is a potent, orally available PKB/Akt inhibitor with an IC50 of 14 nM.
M1900	PHT-427	PHT-427 is a novel dual Akt and PDPK1 inhibitor (Ki of 2.7 μM and 5.2 μM respectively).
M1884	Triciribine	Triciribine (API-2, NSC 154020) is a selective inhibitor of Akt (protein kinase B) signaling with IC50 of 130 nM.
M1862	Ipatasertib (GDC-0068)	GDC-0068 (RG7440) is a potent and selective, ATP-competitive Akt inhibitor with IC50 values of 5 to 18 nM.
M1789	GSK690693	GSK690693 is a potent Akt inhibitor (Akt1 IC50 = 2 nM, Akt2 IC50 = 13 nM, Akt3 IC50 = 9 nM) which also inhibited the phosphorylation of the downstream target GSK3b in cells.
M1654	AT7867	AT7867 is a potent and oral inhibitor of AKT and p70 S6 kinase with an IC50 of 17 nM.
M54588	LY2780301	LY2780301 is an oral dual-target inhibitor of AKT/RSK that binds to and inhibits the activity of Akt, thereby inhibiting the PI3K/Akt signaling pathway, which in turn inhibits cell proliferation and induces apoptosis in tumor cells, and possesses antitumor activity.
M50436	Akt/SKG Substrate Peptide	Akt/SKG Substrate Peptide is a synthetic peptide suitable as a substrate for Akt/PKB, which is not phosphorylated by p70S6K or MAPK1.
M50435	Adropin (34-76) (human, mouse, rat)	Adropin (34-76) (human, mouse, rat) regulates fuel selection preferences in skeletal muscle.
M50434	Apoptin-derived peptide	Apoptin-derived peptide is an antitumor polypeptide with cytotoxicity.
M50433	TAT-TCL1-Akt-in	TAT-TCL1-Akt-in is an Akt inhibitor.
M50432	TCL1(10-24)	TCL1(10-24) is a encompassing the betaA strand of human TCL1.
M49821	IPL344	IPL344 is a bioactive peptide that activates Akt pathway cell signaling and can be used in studies related to amyotrophic lateral sclerosis (ALS).
M49782	Larixol	Larixol is an fMLP inhibitor and also inhibits Src kinase, ERK1/2, p38 and AKT phosphorylation signals in immune regulation.
M49744	Hu7691 hydrochloride	Hu7691 hydrochloride is an orally active, selective Akt inhibitor with IC50s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively.
M49743	Hu7691	Hu7691 is an orally active, selective Akt inhibitor with IC50s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively.
M49742	AKT-IN-11	AKT-IN-11 is one of the most effective antibacterial agents against human hepatoma BEL-7402 cell line with an IC50 value of 1.15μM.
M44752	6-Hydroxyflavone	6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity.
M43375	AKT-IN-17	AKT-IN-17 is a AKt inhibitor.
M43374	Dehydrovomifoliol	Dehydrovomifoliol is a AKT/mTOR dual inhibitor.

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Akt Protein kinase B

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