Akt Protein kinase B

Cat.No.	Name	Information
M1837	MK-2206 2HCl	MK-2206 is a novel allosteric inhibitor of Akt with IC50 values of 8 nM, 12 nM and 65 nM for Akt1, Akt2 and Akt3, respectively.
M3068	TIC10	TIC10 (ONC-201) is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier.
M5167	Calpeptin	Calpeptin is a potent, cell-permeable inhibitor of the Ca²⁺-dependent protease, calpain.
M1823	Perifosine	Perifosine is an orally active Akt inhibitor, the antiproliferative properties of Perifosine with an IC50 of 0.6–8.9 µM.
M2303	Capivasertib (AZD5363)	Capivasertib (AZD5363) is a potentially first-in-class, orally effective pan-AKT inhibitor with strong inhibition against all three AKT isomers (AKT1/2/3) at an IC50 of 3 nM/8 nM/8 nM. It also showed similar inhibitory effect on P70S6K/PKA and low inhibitory activity on ROCK1/2.
M5153	SC79	SC79 is a specific and BBB permeable Akt activator used to enhance Akt activity. SC79 activates Akt in the cytosol and inhibits Akt membrane translocation. SC79 specifically binds to the PH domain of Akt. *The compound is unstable in solutions, freshly prepared is recommended
M22523	Recilisib sodium	Recilisib (ON 01210) sodium is a radioprotectant, which can activate AKT, PI3K activities in cells.
M4988	AKT inhibitor VIII	Akt Inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity (IC50 = 58 nM, 210 nM, and 2.12 μM; respectively).
M54588	LY2780301	LY2780301 is an oral dual-target inhibitor of AKT/RSK that binds to and inhibits the activity of Akt, thereby inhibiting the PI3K/Akt signaling pathway, which in turn inhibits cell proliferation and induces apoptosis in tumor cells, and possesses antitumor activity.
M50436	Akt/SKG Substrate Peptide	Akt/SKG Substrate Peptide is a synthetic peptide suitable as a substrate for Akt/PKB, which is not phosphorylated by p70S6K or MAPK1.
M50434	Apoptin-derived peptide	Apoptin-derived peptide is an antitumor polypeptide with cytotoxicity.
M50433	TAT-TCL1-Akt-in	TAT-TCL1-Akt-in is an Akt inhibitor.
M50432	TCL1(10-24)	TCL1(10-24) is a encompassing the betaA strand of human TCL1.
M49821	IPL344	IPL344 is a bioactive peptide that activates Akt pathway cell signaling and can be used in studies related to amyotrophic lateral sclerosis (ALS).
M49782	Larixol	Larixol is an fMLP inhibitor and also inhibits Src kinase, ERK1/2, p38 and AKT phosphorylation signals in immune regulation.
M49744	Hu7691 hydrochloride	Hu7691 hydrochloride is an orally active, selective Akt inhibitor with IC50s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively.
M49743	Hu7691	Hu7691 is an orally active, selective Akt inhibitor with IC50s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively.
M49742	AKT-IN-11	AKT-IN-11 is one of the most effective antibacterial agents against human hepatoma BEL-7402 cell line with an IC50 value of 1.15μM.
M43375	AKT-IN-17	AKT-IN-17 is a AKt inhibitor.
M43374	Dehydrovomifoliol	Dehydrovomifoliol is a AKT/mTOR dual inhibitor.
M43373	Reptoside	Reptoside, an iridoid glucoside, is a DNA damaging active agent.
M43372	PI3K-IN-48	PI3K-IN-48 is a PI3K inhibitor with IC50 value of 1.55 ± 0.18 μM for A549 cells.
M43371	2-Chlorophenoxazine	2-Chlorophenoxazine is a Akt inhibitor with an IC50 value of 2-5 μM for in vitro.
M43370	AKT-IN-18	AKT-IN-18, an inhibitor of Akt, inhibits Akt with an IC50 of 69.45 μΜ in A549 cells.
M43369	Tubulin/AKT1-IN-1	Tubulin/AKT1-IN-1 is an inhibitor of tubulin polymerization and AKT pathway activation.
M43368	NSC45586	NSC45586 is an inhibitor of pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP).
M43367	AKT-IN-14	AKT-IN-14 is a potent AKTinhibitor with the IC50 values of <0.01 nM, 1.06 nM and 0.66 nM for AKT1, AKT2, AKT3, respectively.
M43366	AKT-IN-14 free base	AKT-IN-14 free baseis a potent AKTinhibitor with the IC50 values of <0.01 nM, 1.06 nM and 0.66 nM for AKT1, AKT2, AKT3, respectively.

By Signaling Pathways

By Product Type

Signaling Pathways

Akt Protein kinase B

Get to Know Us

Customer Support

Resources

Contact Us