Pachymic-acid
| CAS Number | 29070-92-6 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
[5] Baodong Ding, et al. In vitro effect of pachymic acid on the activity of Cytochrome P450 enzymes
| Related Akt Products |
|---|
| 6-Hydroxyflavone
6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. |
| Chemerin-9 (149-157) acetate
Chemerin-9 (149-157) acetate is a potent chemokine-like receptor 1 (CMKLR1) agonist that stimulates the phosphorylation of Akt and ERK as well as the production of reactive oxygen species, ameliorates Aβ1-42-induced memory deficits, modulates the immune response, adipocyte differentiation, and glucose metabolism, and possesses anti-inflammatory activity. |
| AKT-IN-17
AKT-IN-17 is a AKt inhibitor. |
| Dehydrovomifoliol
Dehydrovomifoliol is a AKT/mTOR dual inhibitor. |
| Reptoside
Reptoside, an iridoid glucoside, is a DNA damaging active agent. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
