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Cat. No. M4299
Pachymic-acid Structure

3-O-Acetyltumulosic acid

Size Price Availability Quantity
5mg USD 200  USD200 In stock
10mg USD 320  USD320 In stock
20mg USD 480  USD480 In stock
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Quality Control & Documentation
Biological Activity


Chemical Information
CAS Number 29070-92-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Yuan He, et al. Pachymic Acid Ameliorates Pulmonary Hypertension by Regulating Nrf2-Keap1-ARE Pathway

[2] Jie Zhang, et al. Pharmacokinetic study on the interaction between pachymic acid and bavachin and its potential mechanism

[3] Yanjun Gui, et al. Pachymic acid inhibits inflammation and cell apoptosis in lipopolysaccharide (LPS)-induced rat model with pneumonia by regulating NF-κB and MAPK pathways

[4] Gui-Ping Jiang, et al. Effects and molecular mechanism of pachymic acid on ferroptosis in renal ischemia reperfusion injury

[5] Baodong Ding, et al. In vitro effect of pachymic acid on the activity of Cytochrome P450 enzymes

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Keywords: Pachymic-acid, 3-O-Acetyltumulosic acid supplier, Akt, inhibitors, activators

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