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5-HT Receptor 5-hydroxytryptamine receptor

Cat.No.  Name Information
M2048 Sumatriptan succinate Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache.
M3417 Clozapine Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis.
M2821 Lorcaserin hydrochloride Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM.
M5656 Fluoxetine hydrochloride Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
M14577 Fluoxetine Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research.
M3659 Pimavanserin Pimavanserin is a selective serotonin 5-HT2A inverse agonist.
M6333 3-AQC 3-AQC is a 5-HT 3 antagonist.
M6065 Ziprasidone HCl monohydrate Ziprasidone(CP88059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity.
M6064 Ziprasidone HCl Ziprasidone HCl is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.
M6058 Vortioxetine Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
M6051 Venlafaxine Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.
M6050 Venlafaxine HCl Venlafaxine HCl is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.
M6027 Trazodone hydrochloride Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.
M5992 Tegaserod maleate Tegaserod maleate is a partial agonist of the 5-HT4 receptor; stimulates the peristaltic reflex and accelerates gastrointestinal transit.
M5989 Tandospirone Tandospirone(SM-3997) is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM).
M5956 Sertindole Sertindole, a neuroleptic, is one of the newer antipsychotic medications available.
M5951 Sarpogrelate HCl Sarpogrelate(MCI-9042) hydrochloride, a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD.
M5938 Rizatriptan Benzoate Rizatriptan Benzoate is an agonist at serotonin 5-HT1B and 5-HT1D receptors, used to treat acute migraine attacks.
M5935 Risperidone Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.
M5920 Ramosetron HCl Ramosetron Hydrochloride(YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.
M5884 Pizotifen Pizotifen (Pizotyline) is a potent 5-HT2 receptor antagonist, with a high affinity for 5-HT1C binding site.
M5861 Paroxetine HCl Paroxetine HCl is a potent selective serotonin-reuptake inhibitor, commonly prescribed as an and has GRK2 inhibitory ability with IC50 of 14 μM.
M5835 Ondansetron Hydrochloride Dihydrate Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki=6.16 nM), with low affinity for dopamine receptors.
M5809 Nefazodone HCl Nefazodone hydrochloride is an antidepressant compound.
M5804 Naftidrofuryl oxalate Naftidrofuryl is a drug used in the management of peripheral and cerebral vascular disorders as a vasodilator, enhance cellular oxidative capacity, and may also be a 5-HT2 receptor antagonist.
M5799 Mosapride Citrate Mosapride Citrate is a gastroprokinetic agent that acts as a selective 5HT4 agonist.




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