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Ziprasidone HCl monohydrate

Cat. No. M6065
Ziprasidone HCl monohydrate Structure
Size Price Availability Quantity
10mg USD 60 In stock
50mg USD 150 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Ziprasidone(CP88059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 467.41
Formula C21H24Cl2N4O2S
CAS Number 138982-67-9
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C
References

Nonisothermal kinetics analysis of the dehydration of ziprasidone hydrochloride monohydrate by thermogravimetry.
Ravikiran A, et al. Indian J Pharm Sci. 2013 May;75(3):361-4. PMID: 24082354.

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  Catalog
Abmole Inhibitor Catalog 2017




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