Free shipping on all orders over $ 500

Ziprasidone HCl monohydrate

Cat. No. M6065
Ziprasidone HCl monohydrate Structure
Synonym:

CP 88059

Size Price Availability Quantity
10mg USD 65 In stock
50mg USD 160 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Ziprasidone(CP88059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 467.41
Formula C21H24Cl2N4O2S
CAS Number 138982-67-9
Purity >98%
Solubility 10 mM in DMSO
Storage at -20°C
References

Nonisothermal kinetics analysis of the dehydration of ziprasidone hydrochloride monohydrate by thermogravimetry.
Ravikiran A, et al. Indian J Pharm Sci. 2013 May;75(3):361-4. PMID: 24082354.

Related 5-HT Receptor Products
Idalopirdine hydrochloride

Idalopirdine hydrochloride is a potent and selective 5-HT6 receptor antagonist with a Ki value of 0.83 nM.

PRX-08066

PRX-08066 is a a novel 5-hydroxytryptamine receptor 2B antagonist with IC50 of 3.4 nM.

MIN-101

MIN-101 (Roluperidone) is a novel compound with affinities for 5-HT2A and sigma-2 receptors with Ki values of 7.53 nM and 8.19 nM, respectively.

GSK163090

GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist.

Eptapirone

Eptapirone (F11440) is a potent 5HT(1A) receptor agonist with marked anxiolytic and antidepressant potential.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Ziprasidone HCl monohydrate, CP 88059 supplier, 5-HT Receptor, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.