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Ziprasidone HCl

Cat. No. M6064
Ziprasidone HCl Structure
Synonym:

CP-88059

Size Price Availability Quantity
10mg USD 50 In stock
50mg USD 125 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Ziprasidone HCl is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 449.4
Formula C21H21ClN4OS·HCl
CAS Number 122883-93-6
Purity >99%
Solubility 90 mg/mL in DMSO
Storage at -20°C
References

Ziprasidone Augmentation of Escitalopram for Major Depressive Disorder: Efficacy Results From a Randomized, Double-Blind, Placebo-Controlled Study.
Papakostas GI, et al. Am J Psychiatry. 2015 Dec;172(12):1251-8. PMID: 26085041.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Ziprasidone HCl, CP-88059 supplier, 5-HT Receptor, inhibitors

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