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Naftidrofuryl oxalate

Cat. No. M5804
Naftidrofuryl oxalate Structure
Synonym:

Nafronyl oxalate salt

Size Price Availability Quantity
100mg USD 60 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Naftidrofuryl is a drug used in the management of peripheral and cerebral vascular disorders as a vasodilator, enhance cellular oxidative capacity, and may also be a 5-HT2 receptor antagonist.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 473.56
Formula C26H35NO7
CAS Number 3200-06-4
Purity >98%
Solubility 10 mg/mL in DMSO
Storage at -20°C
References

Cost-effectiveness of cilostazol, naftidrofuryl oxalate, and pentoxifylline for the treatment of intermittent claudication in people with peripheral arterial disease.
Meng Y, et al. Angiology. 2014 Mar;65(3):190-7. PMID: 23378195.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Naftidrofuryl oxalate, Nafronyl oxalate salt supplier, 5-HT Receptor, inhibitors

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