Catalog

5-HT Receptor 5-hydroxytryptamine receptor

Inhibitors

Cat.No.	Name	Information
M6065	Ziprasidone HCl monohydrate	Ziprasidone(CP88059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity.
M6064	Ziprasidone HCl	Ziprasidone HCl is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.
M6058	Vortioxetine	Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
M6051	Venlafaxine	Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.
M6050	Venlafaxine HCl	Venlafaxine HCl is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.
M6027	Trazodone	Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.
M5992	Tegaserod maleate	Tegaserod maleate is a partial agonist of the 5-HT4 receptor; stimulates the peristaltic reflex and accelerates gastrointestinal transit.
M5989	Tandospirone	Tandospirone(SM-3997) is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM).
M5951	Sarpogrelate HCl	Sarpogrelate(MCI-9042) hydrochloride, a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD.
M5938	Rizatriptan Benzoate	Rizatriptan Benzoate is an agonist at serotonin 5-HT1B and 5-HT1D receptors, used to treat acute migraine attacks.
M5935	Risperidone	Risperidone is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder.
M5920	Ramosetron HCl	Ramosetron Hydrochloride(YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.
M5884	Pizotifen	Pizotifen(Pizotyline) is a highly selective 5-HT receptor blocking agent, which is a benzocycloheptane based drug.
M5861	Paroxetine HCl	Paroxetine HCl is an antidepressant drug of the SSRI type.
M5835	Ondansetron Hydrochloride Dihydrate	Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki=6.16 nM), with low affinity for dopamine receptors.
M5804	Naftidrofuryl oxalate	Naftidrofuryl is a drug used in the management of peripheral and cerebral vascular disorders as a vasodilator, enhance cellular oxidative capacity, and may also be a 5-HT2 receptor antagonist.
M5799	Mosapride Citrate	Mosapride Citrate is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
M5798	Mosapride	Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
M5754	Loxapine	Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.
M5660	Fluvoxamine maleate	Fluvoxamine Maleate is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder.
M5548	Dalasetron Mesylate hydrate	Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.
M5543	Cyproheptadine hydrochloride sesquihydrate	Cyproheptadine hydrochloride sesquihydrate is an antihistamine and is an antagonist of serotonin and histamine2.
M5542	Cyproheptadine HCl	Cyproheptadine is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM.
M5475	Cabergoline	Cabergoline, an ergot derivative, is a potent dopamine receptor agonist on D2 receptors.
M5466	Blonanserin	Blonanserin is a relatively selective serotonin (5-HT)2A and dopamine D2 antagonist, used the treatment of schizophrenia.
M5424	Asenapine maleate	Asenapine maleate is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.
M5423	Asenapine	Asenapine(Org 5222) inhibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.
M5400	Alosetron	Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist.
M5214	Lasmiditan	Lasmiditan (also known as COL-144 and LY573144) is a high-affinity, highly selective serotonin (5-HT) 5-HT(1F) receptor agonist.
M5045	Tianeptine	Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo.
M5044	Tianeptine sodium salt	Tianeptine sodium salt is a selective facilitator of 5-HT uptake in vitro and in vivo.
M5022	Almotriptan Malate	Almotriptan Malate is a 5-HT1B/1D-receptor agonist used to treat migraine.
M3985	Triptolide	Triptolide is a structurally unique diterpene triepoxide isolated from a traditional Chinese medicinal plant with anti-inflammatory, immunosuppressive, contraceptive and antitumor activities.
M3909	Glycyrrhizic acid	Glycyrrhizic acid is a widely used anti-inflammatory agent isolated from the licorice root.
M3793	Deferitrin	Deferitrin is a novel, orally available iron chelator, is in the early stage of clinical development for the treatment of chronic iron overload due to transfusional therapy.
M3791	YM 90K hydrochloride	YM 90K hydrochloride is a selective AMPA antagonist with neuro-protective effect. AMPA is a transmembrane glutamate receptor composed of the subunits GluR-1,2,3,4.
M3790	Tasosartan	Tasosartan is a selective, potent, orally active and long-acting nonpeptide Angiotensin II type 1 (AT1) receptor antagonist.
M3782	Oxiracetam	Oxiracetam could decrease neural injury and increase ability of learning, memory and space cognition in traumatic brain injury rats.
M3772	SB242084	SB242084 has a high affinity (pKi 9.0) for the cloned human 5-HT2C receptor and 100- and 158-fold selectivity over the closely related cloned human 5-HT2B and 5-HT2A subtypes respectively.
M3748	Mestanolone	Mestanolone is the 17α-methylated version of dihydrotestosterone (DHT).
M3659	Pimavanserin	Pimavanserin is a selective serotonin 5-HT2A inverse agonist.
M3646	Cyclobenzaprine hydrochloride	Cyclobenzaprine hydrochloride is a skeletal muscle relaxant and a central nervous system (CNS) depressant.
M3585	Tropisetron	Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
M3583	Urapidil hydrochloride	Urapidil hydrochloride is an α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.
M3529	BMY 7378 dihydrochloride	BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pK_i of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pK_i of 8.3.
M3524	BRL-15572	BRL-15572 is a 5-HT1D receptor antagonist with pK_i of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor.
M3481	WAY-100635 Maleate	WAY 100635 is a potent and selective 5-HT1A receptor agonist with pIC50 of 8.87, exhibits >100-fold selectivity against other 5-HT receptor subtypes and major neurotransmitter receptors.
M3479	Aripiprazole	Aripiprazole is a human 5-HT_1A receptor partial agonist with a K_i of 4.2 nM.
M3472	Naratriptan	Naratriptan is a triptan agent that is used for the treatment of migraine headaches.
M3419	Dapoxetine hydrochloride	Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor.

5-HT Receptor 5-hydroxytryptamine receptor

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