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5-HT Receptor 5-hydroxytryptamine receptor

Cat.No.  Name Information
M2048 Sumatriptan succinate Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache.
M3417 Clozapine Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis.
M2821 Lorcaserin hydrochloride Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM.
M5656 Fluoxetine hydrochloride Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
M14577 Fluoxetine Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research.
M3659 Pimavanserin Pimavanserin is a selective serotonin 5-HT2A inverse agonist.
M8955 MIN-101 MIN-101 (Roluperidone) is a novel compound with affinities for 5-HT2A and sigma-2 receptors with Ki values of 7.53 nM and 8.19 nM, respectively.
M8942 GSK163090 GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist.
M8932 Eptapirone Eptapirone (F11440) is a potent 5HT(1A) receptor agonist with marked anxiolytic and antidepressant potential.
M8900 TG6-10-1 TG6-10-1 is a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2.
M8864 Zotepine Zotepine is a potent 5-HT2A, 5-HT2C, histamine H1, α1-adrenergic, and dopamine D2 receptor antagonist with Kd values of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively.
M8861 Xaliproden hydrochloride 5-HT1A serotonin receptor agonist; neuroprotectant.
M8566 Eltoprazine hydrochloride Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients.
M8503 SB-207266 SB-207266 is a potent, selective, orally active and long-acting 5-HT4 antagonist in vivo.
M8091 PF-04995274 PF-04995274 is a potent partial agonist of serotonin 5HT4 receptor with Ki = 0.
M7763 Diacylglycerol Kinase Inhibitor I Diacylglycerol Kinase Inhibitor I (R 59-022) is an inhibitor of Diacylglycerol Kinase (DGK) and 5-HT Receptor with an IC50 value of 2.8 µM for DGK and inhibits the phosphorylation of OAG to OAPA.In addition, Diacylglycerol Kinase Inhibitor I also activates protein kinase C (PKC). In addition, Diacylglycerol Kinase Kinase Inhibitor I also activates protein kinase C (PKC).
M7684 Clozapine N-oxide Clozapine N-oxide (CNO) is a 5-HT2 serotonin receptor antagonist; major metabolite of clopazine that can be monitored by HPLC.
M7259 SB 228357 SB 228357 is a 5-HT 2C/2B antagonist/inverse agonist.
M7248 SB 200646 hydrochloride SB 200646 hydrochloride is a 5-HT 2C/2B antagonist.
M7226 RS 67333 hydrochloride RS 67333 hydrochloride is a 5-HT 4 partial agonist.
M6984 MM 77 dihydrochloride MM 77 dihydrochloride is a 5-HT 1A (postsynaptic) antagonist.
M6946 Melperone hydrochloride Melperone hydrochloride is a 5-HT2A/D2 receptor antagonist; neuroleptic.
M6933 LY334370 LY 334370 is a selective 5-HT1F agonist.
M6760 GR 127935 hydrochloride GR 127935 hydrochloride is a potent, selective 5-HT 1B/1D antagonist.
M6759 GR 113808 GR 113808 is a potent, selective 5-HT 4 antagonist.
M6343 4F 4PP oxalate 4F 4PP oxalate is a selective 5-HT 2A antagonist.




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