Cat.No. | Name | Information |
---|---|---|
M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist. |
M8955 | MIN-101 | MIN-101 (Roluperidone) is a novel compound with affinities for 5-HT2A and sigma-2 receptors with Ki values of 7.53 nM and 8.19 nM, respectively. |
M8942 | GSK163090 | GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist. |
M8932 | Eptapirone | Eptapirone (F11440) is a potent 5HT(1A) receptor agonist with marked anxiolytic and antidepressant potential. |
M8900 | TG6-10-1 | TG6-10-1 is a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2. |
M8864 | Zotepine | Zotepine is a potent 5-HT2A, 5-HT2C, histamine H1, α1-adrenergic, and dopamine D2 receptor antagonist with Kd values of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. |
M8861 | Xaliproden hydrochloride | 5-HT1A serotonin receptor agonist; neuroprotectant. |
M8566 | Eltoprazine hydrochloride | Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients. |
M8503 | SB-207266 | SB-207266 is a potent, selective, orally active and long-acting 5-HT4 antagonist in vivo. |
M8091 | PF-04995274 | PF-04995274 is a potent partial agonist of serotonin 5HT4 receptor with Ki = 0. |
M7763 | Diacylglycerol Kinase Inhibitor I | Diacylglycerol Kinase Inhibitor I (R 59-022) is an inhibitor of Diacylglycerol Kinase (DGK) and 5-HT Receptor with an IC50 value of 2.8 µM for DGK and inhibits the phosphorylation of OAG to OAPA.In addition, Diacylglycerol Kinase Inhibitor I also activates protein kinase C (PKC). In addition, Diacylglycerol Kinase Kinase Inhibitor I also activates protein kinase C (PKC). |
M7684 | Clozapine N-oxide | Clozapine N-oxide (CNO) is a 5-HT2 serotonin receptor antagonist; major metabolite of clopazine that can be monitored by HPLC. |
M7259 | SB 228357 | SB 228357 is a 5-HT 2C/2B antagonist/inverse agonist. |
M7248 | SB 200646 hydrochloride | SB 200646 hydrochloride is a 5-HT 2C/2B antagonist. |
M7226 | RS 67333 hydrochloride | RS 67333 hydrochloride is a 5-HT 4 partial agonist. |
M6984 | MM 77 dihydrochloride | MM 77 dihydrochloride is a 5-HT 1A (postsynaptic) antagonist. |
M6946 | Melperone hydrochloride | Melperone hydrochloride is a 5-HT2A/D2 receptor antagonist; neuroleptic. |
M6933 | LY334370 | LY 334370 is a selective 5-HT1F agonist. |
M6760 | GR 127935 hydrochloride | GR 127935 hydrochloride is a potent, selective 5-HT 1B/1D antagonist. |
M6759 | GR 113808 | GR 113808 is a potent, selective 5-HT 4 antagonist. |
M6343 | 4F 4PP oxalate | 4F 4PP oxalate is a selective 5-HT 2A antagonist. |
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