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Mosapride Citrate

Cat. No. M5799
Mosapride Citrate Structure
Synonym:

AS-4370

Size Price Availability Quantity
10mg USD 75 In stock
50mg USD 155 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Mosapride Citrate is a gastroprokinetic agent that acts as a selective 5HT4 agonist.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 614.02
Formula C21H25ClFN3O3.C6H8O7
CAS Number 112885-42-4
Purity >99%
Solubility 90 mg/mL in DMSO
Storage at -20°C
References

Mosapride citrate increases postprandial glucagon-like peptide-1, insulin, and gene expression of sweet taste receptors.
Maruoka D, et al. Dig Dis Sci. 2015 Feb;60(2):345-53. PMID: 25008428.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Mosapride Citrate, AS-4370 supplier, 5-HT Receptor, inhibitors

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