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Trazodone

Cat. No. M6027
Trazodone  Structure
Synonym:

AF-1161, KB-831

Size Price Availability Quantity
100mg USD 75 In stock
500mg USD 100 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 408.32
Formula C19H22ClN5O.HCl
CAS Number 25332-39-2
Purity >98%
Solubility 4 mg/mL warmed in DMSO
Storage at -20°C
References

Postmortem distribution of trazodone concentrations.
McIntyre IM, et al. Forensic Sci Int. 2015 Jun;251:195-201. PMID: 25912183.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Trazodone , AF-1161, KB-831 supplier, 5-HT Receptor, inhibitors

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