Animal Modeling

Cat.No.	Name	Information
M1969	Doxorubicin HCL	Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
M2082	Streptozotocin	Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended
M2227	Imiquimod	Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity.
M5152	Sodium Butyrate	Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis.
M5791	Mitomycin C	Mitomycin C (Ametycine) is an antineoplastic antibiotic by inhibiting DNA synthesis.
M3637	Puromycin dihydrochloride	Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor.
M6033	Dihydrotestosterone	Dihydrotestosterone is an androgen (male hormone). Specifically it's the strongest of the androgens. It can be used to construct animal models of polycystic ovary syndrome (PCOS).
M3699	Letrozole	Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer.
M5688	Heparin sodium	Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
M9524	Lipopolysaccharides	Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5.
M5666	Furazolidone	Furazolidone is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria. It can be used to construct animal models of cardiomyopathy.
M5647	Finasteride	Finasteride is an orally active, potent and reversible steroid type II 5α-reductase (SRD5A2) inhibitor with an IC50 value of 4.2 nM.Finasteride can be used in the construction of animal models of hypospadias.
M5519	Cilostazol	Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake. It can be used to construct animal models of deep vein thrombosis.
M5435	Azathioprine	Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases. It can be used to construct animal models of colitis.
M5426	Aspirin	Aspirin is a salicylate, and irreversible COX1 and COX2 inhibitor, used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication.
M5368	4-Aminopyridine	4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.
M5365	Monobenzone	Monobenzone is a potent skin depigmenting agent that specifically inhibits tyrosinase and can be used in the construction of animal models of vitiligo and in studies related to skin pigmentation loss.
M4942	Metoclopramide hydrochloride hydrate	Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic. It can be used to construct animal models of hyperprolactinemia.
M4901	Chloramphenicol	Chloramphenicol is a bacteriostatic by inhibiting protein synthesis. It can be used to construct animal models of aplastic anemia.
M4663	Reserpine	Reserpine is an inhibitor of vesicular monoamine transporter protein 2 (VMAT2) that irreversibly blocks the H+-coupled vesicular monoamine transporters, VMAT1 and VMAT2. It can be used to construct animal models of depression.
M4282	Crotaline (Monocrotaline)	Crotaline is an pyrrolizidine alkaloid extracted from the seeds of the Crotalaria spectabilis plant to induce pulmonary hypertension in rodents.
M3891	Calcipotriol	Calcipotriol is a 1,25-Dihydroxyvitamin D3 analogue which is used for the research of psoriasis. *The compound is unstable in solutions, freshly prepared is recommended
M3826	Papain	Papain is a cysteine protease of the peptidase C1 family.
M3738	Oxonic acid potassium salt	Oxonic acid potassium salt is an inhibitor of uricase.
M3521	Fluticasone propionate	Fluticasone propionate (Flonase, Veramyst) is a synthetic corticosteroid which is derived from fluticasone used to treat asthma and allergic rhinitis (hay fever).
M3463	Prednisolone	Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. It can be used to construct autoimmune hepatitis models.
M3453	Scopolamine hydrobromide	Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.It can be used to construct animal models of dry eye.
M3384	Diethylstilbestrol	Diethylstilbestrol is a synthetic nonsteroidal estrogen that can be used to construct animal models of primary dysmenorrhea.
M3325	Captopril	Captopril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM. It can be used to construct animal models of heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM.
M3301	Acetaminophen	Acetaminophen is a COX inhibitor for COX-1 and COX-2 with IC50 of 113.7 μM and 25.8 μM, respectively. *The compound is unstable in solutions, freshly prepared is recommended

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