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Animal Modeling

Cat.No.  Name Information
M1969 Doxorubicin HCL Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
M2082 Streptozotocin Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended
M2227 Imiquimod Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity.
M5152 Sodium Butyrate Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis.
M5791 Mitomycin C Mitomycin C (Ametycine) is an antineoplastic antibiotic by inhibiting DNA synthesis.
M3637 Puromycin dihydrochloride Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor.
M6033 Dihydrotestosterone Dihydrotestosterone is an androgen (male hormone). Specifically it's the strongest of the androgens. It can be used to construct animal models of polycystic ovary syndrome (PCOS).
M3699 Letrozole Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer.
M5688 Heparin sodium Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
M9524 Lipopolysaccharides Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5.
M14800 L-Thyroxine sodium L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4).
M13641 Bleomycin hydrochloride Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic.
M13340 Uric acid Uric acid is a scavenger of oxygen radical, a very important antioxidant and a product of the metabolic decomposition of purine nucleotides. Helps maintain stable blood pressure and fights oxidative stress. Uric acid removes reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite and inhibits lipid peroxidation. It can be used to induce animal models of uric acid nephropathy.
M11554 Pristane Pristane (Norphytane) is a naturally saturated terpene alkane found in small amounts in many plants, various Marine organisms, and is the most active component in mineral oils. Pristane is a non-antigenic adjuvant that induces MHC Class II restrictive arthritis T cells in rats.
M11540 Propranolol Propranolol is a non-selective β-adrenergic receptor (βAR) antagonist, which has high affinity for β1AR and β2AR with Ki value of 1.8 nM and 0.8 nM, respectively. Propranolol inhibited the binding of [3H]-DHA to rat meninges with an IC50 of 12 nM. It can be used to construct animal models of psoriasis.
M11502 Hydroquinone Hydroquinone is an inhibitor and antioxidant used as a synthetic intermediate in dyes, engine fuels, and oils. It also has antioxidant properties and produces toxic effects in multiple organs, especially the kidneys. It can be used to construct animal models of vitiligo.
M11477 Colcemid Colcemid (Demecolcine) is an effective mitotic inhibitor. Colcemid binds tubulin and blocks cells for metaphase karyotype analysis. Colcemid can induce apoptosis and can be used in tumor research.
M11029 Thioacetamide Thioacetamide (TAA), a hepatotoxin commonly used for experimental purposes, causes necrosis in the center of the lobule after a single administration and can be used to construct animal models of liver injury.
M10552 β-Aminopropionitrile (Liquid) β-Aminopropionitrile is a specific and irreversible lysyl oxidase (LOX) inhibitor.
M10449 Oleic acid (Liquid) Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is also a Na+/K+ ATPase activator.
M10355 Uric acid sodium Uric acid sodium is a scavenger of oxygen radical, it is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress.
M10341 Lauric acid Lauric acid is a middle chain-free fatty acid with strong bactericidal properties.
M10276 Elastase (from porcine pancreas) Elastase from porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide.
M10195 MOG (35-55) (Mouse, rat) MOG (35-55) (Mouse, rat) is a minor component of CNS myelin.
M10041 MPP+ iodide MPP+ iodide is a toxic metabolite of the neurotoxin MPTP, MPP+ iodide causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra.
M9977 Lithium chloride Lithium chloride can be used to induce epilepsy model.
M9976 D-Galactose D-Galactose is a natural aldohexose and C-4 epimer of glucose, it accelerates the aging of invertebrates and mammals and is used as a model of aging.
M9975 7,12-Dimethylbenz[a]anthracene 7,12-Dimethylbenz[a]anthracene is a polycyclic aromatic hydrocarbon.
M9974 L-Methionine L-Methionine is an essential amino acid for metabolism.
M9972 Alloxan monohydrate Alloxan monohydrate is a kind of hydrated alloxan, it can be used to induce diabetes model research.




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