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Animal Modeling

Cat.No.  Name Information
M1969 Doxorubicin HCL Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
M2082 Streptozotocin Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended
M2227 Imiquimod Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity.
M5152 Sodium Butyrate Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis.
M5791 Mitomycin C Mitomycin C (Ametycine) is an antineoplastic antibiotic by inhibiting DNA synthesis.
M3637 Puromycin dihydrochloride Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor.
M6033 Dihydrotestosterone Dihydrotestosterone is an androgen (male hormone). Specifically it's the strongest of the androgens. It can be used to construct animal models of polycystic ovary syndrome (PCOS).
M3699 Letrozole Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer.
M5688 Heparin sodium Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
M9524 Lipopolysaccharides Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5.
M40783 p-Chloroamphetamine hydrochloride p-Chloroamphetamine hydrochloride, a neurotoxin that destroys serotonergic neurons, can be used to construct animal models of premature ejaculation.
M40478 Scopolamine hydrochloride Scopolamine hydrochloride is a non-selective and high affinity (≤1 nM) muscarinic antagonist that is used for the prevention of post-operative nausea and vomiting. Scopolamine readily passes the blood brain barrier. Scopolamine also reversibly inhibits 5-HT3 receptor-responses with an IC50 of 2.09 μM.
M25572 Morrhuate sodium Morrhuate sodium is the sodium salt of fatty acids in cod liver oil and can be used to construct rabbit osteomyelitis models.
M25570 Coal Tar Coal Tar is a product obtained from the dry distillation process of coal and can be used to construct a rabbit ear acne model.
M6863 Kainic acid Kainic acid is a potent excitotoxic agent and neurotoxin, as well as an agonist of the ionotropic glutamate receptor subtype. In addition, Kainic acid can be used to construct animal models of epilepsy.




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