About 30 results found for searched term "c-Met" (0.006 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1757 | XL-184 | c-Met |
| Cabozantinib, BMS-907351，Cabometyx | ||
| XL184 is a small molecule inhibits multiple receptor tyrosine kinases, specifically MET and VEGFR2 with IC50 values of 0.035 and 1.8 nM for VEGFR2 and Met respectively. | ||
| M2198 | Curcumin | Histone Acetyltransferase |
| Indian Saffron; Turmeric yellow; Natural Yellow 3; Diferuloylmethane | ||
| Curcumin (Diferuloyl), a natural phenolic compound, is a p300/CREB binding protein specific inhibitor that inhibits histone/non-histone acetylation and histone acetyltransferase-dependent chromatin transcription. Curcumin inhibited NF-κ B and MAPKs, and had anti-inflammatory, antioxidant, anti-proliferation and anti-angiogenesis effects. Curcumin induces Nrf2 protein stabilization through Keap1 cysteine modification. | ||
| M11366 | Se-Methylselenocysteine | Apoptosis |
| Methylselenocysteine; Se-Methylseleno-L-cysteine | ||
| Se-methylselenocysteine, a precursor of methyl selenium, has strong cancer chemoprophylaxis and antioxidant activity. Se-Methylselenocysteine has oral biological activity, can induce apoptosis. | ||
| M2220 | GDC-0941 Bimesylate | PI3K |
| Pictilisib dimethanesulfonate; GDC-0941 (2 MeSO3H salt); GDC-0941 | ||
| GDC-0941 Bimesylate is the orally bioavailable bismesylate salt of a potent inhibitor of the class I phosphatidylinositol 3 kinase (PI3K). | ||
| M2226 | Melatonin | Melatonin Receptor |
| Melatonex; N-Acetyl-5-methoxytryptamine; MT | ||
| Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. | ||
| M2432 | Bardoxolone Methyl | IκB/IKK |
| RTA 402, TP-155, NSC 713200,CDDO Methyl ester | ||
| Bardoxolone Methyl is an IKK inhibitor with potent pro-apoptotic and anti-inflammatory activities, as well as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway. | ||
| M2502 | Cetrimonium Bromide | Nucleic Acid Extraction and Purification |
| Cetyltrimethylammonium Bromide; Hexadecyltrimethylammonium bromide; CTAB | ||
| Cetrimonium Bromide is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts. | ||
| M2512 | Chlorquinaldol | Antibiotic |
| 5,7-Dichloro-8-hydroxy-2-methylquinoline | ||
| Chlorquinaldol is an antimicrobial agent used for local antisepsy. | ||
| M2529 | Clofibric Acid (PCIB) | PPAR |
| 2-(4-Chlorophenoxy)-2-methylpropionic acid; Chlorofibrinic acid | ||
| Clofibric acid (PCIB, Chlorofibrinic acid), a lipid fiber modulator Clofibrate, Etofibrate and Etofyllinclofibrate active metabolites, is a PPARα excitant, has the effect of lowering blood lipid. Clofibric acid is also a herbicide. | ||
| M2615 | Decamethonium Bromide | AChR/AChE |
| Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent. | ||
| M2714 | Fosfomycin Tromethamine | Antibiotic |
| Fosfomycin trometamol | ||
| Fosfomycin tromethamine is a phosphonic acid antibiotic that crosses the blood-brain barrier, inhibits bacterial cell wall synthesis, and has broad-spectrum antimicrobial activity, with in vitro activity against most urinary tract pathogens. | ||
| M3254 | Pyrimethamine | Antifolate |
| Pirimecidan; Pirimetamin; RP 4753 | ||
| Pyrimethamine is a dihydrofolate reductase(DHFR) inhibitor with an IC50 of 15.4 nM. | ||
| M3265 | Olmesartan | Angiotensin Receptor |
| Benicar, Olmetec | ||
| Olmesartan is an angiotensin II receptor antagonist with an IC50 of 7.7 nM. | ||
| M3309 | Bethanechol chloride | AChR/AChE |
| Carbamyl-β-methylcholine chloride | ||
| Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors. | ||
| M3385 | Cimetidine | Histamine Receptor |
| SKF-92334 | ||
| Cimetidine, a histamine congener, competitively inhibits histamine binding to histamine H2 receptors. | ||
| M3471 | Ketorolac | COX |
| Ketorolac tris salt; Ketorolac Tromethamine | ||
| Ketorolac (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively. | ||
| M3573 | Cefditoren Pivoxil | Antibiotic |
| Cefditoren pivoxyl; Cefditoren pivaloyloxymethyl ester; ME 1207 | ||
| Cefditoren Pivoxil is used to treat uncomplicated skin and skin structure infections, etc. | ||
| M3589 | Methscopolamine bromide | AChR/AChE |
| (-)-Scopolamine methyl bromide; Hyoscine methyl bromide | ||
| Methscopolamine is a muscarinic acetylcholine receptor blocker. | ||
| M3598 | Penicillamine | Others |
| DL-beta-Mercaptovaline, 3,3-Dimethyl-DL-cysteine, 3-Sulfanylvaline, Cuprimine, Depen, DL-PenA | ||
| Penicillamine is used as an antirheumatic and as a chelating agent in Wilson’s disease. | ||
| M3626 | Cobimetinib (GDC-0973) | MEK |
| Cobimetinib ; XL518 | ||
| Cobimetinib (GDC-0973, RG7420) is an effective, selective, oral MEK1 inhibitor with an IC50 of 4.2 nM against MEK1. In addition, Cobimetinib is an inhibitor of Akt. | ||
| M3779 | Sancycline | Antibiotic |
| Bonomycin; 6-Demethyl-6-deoxytetracycline | ||
| Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin. | ||
| M3877 | 4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine | Others |
| 4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine | ||
| M4332 | Paederosidic-acid-methyl-ester | Potassium Channel |
| Paederosidic acid Methyl ester, an ATP-sensitive K+ Channel activator, was isolated from P. scandens. Paederosidic acid Methyl ester has shown significant central pain-relieving activity, increasing pain thresholds by activating ATP-sensitive K+ channels in the brain and spinal cord levels. | ||
| M4345 | Barlerin | NF-κB |
| 8-O-Acetyl shanzhiside methyl ester | ||
| Barlerin (8-O-acetyl Shanzhiside methyl ester) is a cyclosporin glucoside isolated from folk medicinal plants in Xizang, China. Barlerin (8-O-acetyl Shanzhiside methyl ester) inhibited NF-κB activity. | ||
| M4392 | Scutellarin-methylester | Others |
| Scutellarin Methyl ester is a component of breviscapine, a crude extract of several flavonoids in breviscapine. | ||
| M4424 | Tetramethylpyrazine (2,3,5,6-Tetramethylpyrazine) | Apoptosis |
| Chuanxiongzine; Tetramethylpyrazine；Ligustrazine | ||
| Tetramethylpyrazine (2,3,5,6-Tetramethylpyrazine) is an alkyl pyrazine extracted from Ligusticum wallichii (Chuan Xiong), often used as a flavor in French fries, bread, tea, dairy products, bean products and other food. Ligustrazine has potential antineural and anti-inflammatory activities in rats. | ||
| M4460 | Oroxylin-A | CDK |
| Baicalein 6-methyl ether; 6-Methoxybaicalein | ||
| Oroxylin A is an active flavonoid that inhibits the phosphorylation of MDM2 and SIRT1 through the inhibition of CDK9, thus inhibiting MDM2-mediated degradation of P53 and SIRT1-mediated deacetylation of P53, and ultimately stabilizing the P53 protein.Oroxylin A has strong anticancer activity. | ||
| M4487 | Peucedanol | Antibiotic |
| Peucedanol methyl ether | ||
| Ulopterol, a coumarin isolated from the leaves of Toddalia Asiatica (L.) Lam, has strong antibacterial and antifungal activities. | ||
| M4963 | 2,3-Dichloro-5-(trifluoromethyl)pyridine | Others |
| In the crystal structure, centrosymmetric dimers arise from pairs of N-H⋯N hydrogen bonds. | ||
| M5114 | Calcein-AM | Fluorescent Dye |
| Calcein acetoxymethyl ester | ||
| Calcein-am is a fluorescent dye that penetrates cells and is used to measure cell viability. The excitation and emission wavelengths of Calcein are 494 nm and 517 nm, respectively. Fluorescent green. Store at -20℃ away from light. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
