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Paederosidic-acid-methyl-ester

Cat. No. M4332

All AbMole products are for research use only, cannot be used for human consumption.

Paederosidic-acid-methyl-ester Structure
Size Price Availability Quantity
5mg USD 165  USD165 In stock
10mg USD 270  USD270 In stock
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Quality Control & Documentation
Biological Activity

Paederosidic acid Methyl ester, an ATP-sensitive K+ Channel activator, was isolated from P. scandens. Paederosidic acid Methyl ester has shown significant central pain-relieving activity, increasing pain thresholds by activating ATP-sensitive K+ channels in the brain and spinal cord levels.

Chemical Information
Molecular Weight 478.47
Formula C19H26O12S
CAS Number 122413-01-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yu-Feng Chen, et al. Possible mechanism involved in the antinociceptive activity of dimer of paederosidic acid and paederosidic acid methyl ester in mice

[2] Weixin Jiang, et al. Characterization of multiple absorbed constituents in rats after oral administration of Paederia scandens decoction

[3] Ying Ma, et al. Effects of extracts from Paederia scandens (LOUR.) MERRILL (Rubiaceae) on MSU crystal-induced rats gouty arthritis

[4] Yu-Feng Chen, et al. Antinociceptive activity of Paederosidic Acid Methyl Ester (PAME) from the n-butanol fraction of Paederia scandens in mice

[5] Xu Zou, et al. Studies on chemical constituents of Paederia scandense

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Keywords: Paederosidic-acid-methyl-ester supplier, Potassium Channel, inhibitors, activators

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