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Cetrimonium Bromide

Cat. No. M2502
Cetrimonium Bromide  Structure
Synonym:

Cetyltrimethylammonium Bromide; Hexadecyltrimethylammonium bromide; CTAB

Size Price Availability Quantity
100mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Cetrimonium Bromide is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts.

Chemical Information
Molecular Weight 364.45
Formula C19H42N.Br
CAS Number 57-09-0
Solubility (25°C) DMSO 5 mg/mL
Water 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Zhenxing Liu, et al. Cetrimonium bromide promotes the clearance of lipids by activating the TFEB-mediated autophagosome-lysosome pathway in hepatic cells

[2] Tsai-Kun Wu, et al. Cetrimonium Bromide Inhibits Cell Migration and Invasion of Human Hepatic SK-HEP-1 Cells Through Modulating the Canonical and Non-canonical TGF-β Signaling Pathways

[3] Zeinab Saberi, et al. Fluorometric label-free aptasensor for detection of the pesticide acetamiprid by using cationic carbon dots prepared with cetrimonium bromide

[4] Maricarmen Iiguez-Moreno, et al. Biofilm formation by Staphylococcus aureus and Salmonella spp. under mono and dual-species conditions and their sensitivity to cetrimonium bromide, peracetic acid and sodium hypochlorite

[5] Richard J Simpson. CTAB-PAGE

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Keywords: Cetrimonium Bromide , Cetyltrimethylammonium Bromide; Hexadecyltrimethylammonium bromide; CTAB supplier, Nucleic Acid Extraction and Purification, inhibitors, activators


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